A Case of Giant Epidermoid Cyst in the Floor of the Mouth That Caused Severe Obstructive Sleep Apnea Syndrome


We describe here, a case with a giant epidermoid cyst in the floor of the mouth that caused severe obstructive sleep apnea syndrome (OSAS). A 37-year-old man was referred to our clinic because of a swelling in the floor of his mouth and sleep apnea syndrome. The occurrence of breathing disorders and daytime drowsiness was monitored to evaluate his OSAS 1 day before and 7 days after surgery. Before surgery, the apnea-hyponea index (AHI) and Epworth Sleepiness Scale (ESS) were 45.7 and 22, respectively. The clinical diagnosis was a dermoid or an epidermoid cyst that caused severe OSAS. Under general anesthesia, the patient underwent intraoral surgical removal of the cyst, along with aspiration to reduce the mass. After surgery, his sleep apnea syndrome was significantly improved. The postoperative AHI and ESS were 5.5 and 7, respectively. As of 2 years after the operation, there was no evidence of recurrence.

Share and Cite:

Nakamoto, N. , Sato, T. , Sano, Y. , Kabeya, M. , Enoki, Y. , Sakata, Y. and Yoda, T. (2014) A Case of Giant Epidermoid Cyst in the Floor of the Mouth That Caused Severe Obstructive Sleep Apnea Syndrome. Open Journal of Stomatology, 4, 243-248. doi: 10.4236/ojst.2014.45034.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Turetschek, K., Hospodka, H. and Steiner, E. (1995) Case Report: Epidermoid Cyst of the Floor of the Mouth: Diagnostic Imaging by Sonography, Computed Tomography and Magnetic Resonance Imaging. The British Journal of Radiology, 68, 205-207.
[2] Rajayogeswaran, V. and Eveson, J.W. (1989) Epidermoid Cyst of the Buccal Mucosa. Oral Surgery, Oral Medicine, Oral Pathology, 67, 181-184.
[3] Calderon, S. and Kaplan, I. (1993) Concomitant Sublingual and Submentalepidermoid Cysts: A Case Report. Journal of Oral and Maxillofacial Surgery, 51, 790-792.
[4] Walstad, W.R., Solomon, J.M., Schow, S.R. and Ochs, M.W. (1998) Midline Cystic Lesion of the Floor of the Mouth. Journal of Oral and Maxillofacial Surgery, 56, 70-74.
[5] Koca, H., Seckin, T., Sipahi, A. and Kazanc, A. (2007) Epidermoid Cyst in the Floor of the Mouth: Report of a Case. Quintessence International, 38, 473-477.
[6] Bitar, M.A. and Kumar, S. (2003) Plunging Congenital Epidermoid Cyst of the Oral Cavity. European Archives of Oto-Rhino-Laryngology, 260, 223-225.
[7] Guilleminault, C. and Eldridge, F.L. (1973) Insomnia with Sleep Apnea: A New Syndrome. Science, 181, 856-858.
[8] Strollo, P.J. and Rogers, R.M. (1996) Obstructive Sleep Apnea. The New England Journal of Medicine, 334, 99-104.
[9] Laube, I., Seeger, R., Russi, E.W. and Bloch, K.E. (1998) Accidents Related to Sleepiness: Review of Medical Causes and Prevention with Special Reference to Switzerland. Schweizerische Medizinische Wochenschrift, 128, 1487-1499.
[10] Kushida, C.A., Littner, M.R., Morgenthaler, T., Alessi, C.A., Bailey, D. and Coleman Jr., J. (2005) Practice Parameters for the Indications for Polysomnography and Related Procedures: An Update for 2005. Sleep, 28, 499-521.
[11] Longo, F., Maremonti, P., Mangone, G.M., De Maria, G. and Califano, L. (2003) Midline (Dermoid) Cysts of the Floor of the Mouth: Report of 16 Cases and Review of Surgical Techniques. Plastic & Reconstructive Surgery, 112, 1560-1565.
[12] Lowry, R.E., Tempero, R.M. and Davis, L.F. (1979) Epidermoid Cyst of the Floor of the Mouth. Journal of Oral Surgery, 37, 271-273.
[13] Akao, I., Nobukiyo, S., Kobayashi, T., Kikuchi, H. and Koizuka, I. (2003) A Case of Large Dermoid Cyst in the Floor of the Mouth. Auris Nasus Larynx, 30, 137-139.
[14] El-Hakim, I.E. and Alyamani, A. (2008) Alternative Surgical Approaches for Excision of Dermoid Cyst of the Floor of Mouth. International Journal of Oral and Maxillofacial Surgery, 37, 497-499.

Copyright © 2022 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.