Is Alzheimer’s Disease an Irreversible Loss of Memory Function with No Hope of Return?


Since Socrates memory has always been an intriguing matter. To date for the common run of people being hit by Alzheimer’s disease (AD) is “memory loss with no hope of return”. Looking at the brain matter as an ordered closed system where memory and cognition information are located, according to Loschmidt Paradox, and thermodynamically speaking, it should be possible for AD patient brains presenting severe cognitive impairments (disordered state), to move backward to the original brain ordered state. This assumption based on thermodynamic concepts may appear inconsistent with current knowledge in neurosciences on “memory and its operation”. Attempts to connect neurobiological science to quantum physics concepts may allow a breakthrough in the understanding of memory function and therefore a step ahead in the knowledge of how memory works.

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Kraus, J. (2014). Is Alzheimer’s Disease an Irreversible Loss of Memory Function with No Hope of Return?. Psychology, 5, 365-368. doi: 10.4236/psych.2014.55047.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Bergson, H. (1896). Essay on the Relation of Body and Spirit. (Translators N. M. Paul and W. S. Palmer). Matiere et Memoire. Zone Books.
[2] Berut, A., Arakelyan, A., Petrosyan, A., Ciliberto, S., Dillenschneider, R., & Lutz, E. (2012). Experimental Verification of Landauer’s Principle Linking Information and Thermodynamics. Nature, 483,187-189
[3] Bostock, D. (1988). Plato’s Theaetetus. Oxford: The Clarendon Press.
[4] Cifra, M., Fields, J., & Farhadi, A. (2011). Electromagnetic Cellular Interactions. Progress in Biophysics and Molecular Biology, 105, 223-246.
[5] Cucic, D. (2009). Paradoxes of Thermodynamics and Statiscal Physics.
[6] De Grey, A. D. N. J., & Rae, M. (2007). Ending Aging: The Rejuvenation Biotechnologies That Could Reverse Human Aging in Our Lifetime (416 p). New York, NY: St. Martin’s Press.
[7] Hasan, T., Hernández-González, S., Dogbevia, G., Trevino, M., Bertocchi, I., Gruart, A., & Delgado-Garcia, J.-M. (2013). Role of Motor Cortex NMDA Receptors in Learning-Dependent Synaptic Plasticity of Behaving Mice. Nature Communications, 27.
[8] Kak, S. (2013). Biological Memories and Agents as Quantum Collectives. Neuro Quantology, 11, 391-398.
[9] Kirschvink, J., Kobashi-Kirschvink, A., & Woodford, B. (1992). Magnetite Biomineralization in Human Brain. Proceedings of the National Academy of Sciences of the United States of America, 89, 7683-7687.
[10] Loschmidt, J. (1876). Zur Grosse der Luftmoleciile, Sitzungsber. Kais.Akad.Wiss.Wien, Math. Naturwiss.Classe, 52, 395.
[11] Pavlopoulos, E., Jones, S., Kosmidis, S., Close, M., Kim, C., Kovalerchik, O., Small, S., & Kandel, E. (2013). Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48. Science Translational Medicine, 5, 200ra115.
[12] Sirdeshmukh, D.B., Sirdeshmukh, L., & Subhadra, K. G. (2001). Alkali Halides: A Handbook of Physical Properties (pp. 65, 68). Berlin: Springer.

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