Effect of Short-Term Whole-Body Vibration Training on Metabolic Risk Factors, Inflammatory Markers, and Arterial Stiffness


To investigate the effect of aerobic exercise combined with whole-body vibration (WBV) training on metabolic syndrome risk, and inflammatory markers, and to compare its effects on arterial stiffness and several blood parameters related to metabolic syndrome with those of aerobic training alone. Thirty healthy participants were divided into 2 groups matched for age and body mass index (BMI). Fifteen subjects were assigned to the WBV group (WBV + aerobic training) and the other 15 to the control group (aerobic training only). All participants performed a treadmill exercise 3 days/week for 4 weeks, for 50 min after 30 min rest period. Exercise was performed at a heart rate (HR) corresponding to 60% of the HR at each individual’s maximum oxygen uptake (VO2max). Body weight and BMI after training were significantly lower than those before training in the WBV group (P < 0.01). Concerning arterial stiffness, the pulse-wave velocity after training was significantly lower than that before training in the WBV group (1048.7 ± 105.6 vs. 1008.4 ± 101.1 cm/s, P < 0.05). Meanwhile, the VO2max after training was significantly higher than that before training in the WBV group (47.7 ± 12.8 vs. 51.4 ± 14.1 mL·min-1·kg-1, P < 0.01). However, no significant differences were observed in any parameters before and after training in the control group. Our results suggest that aerobic exercise combined with WBV training may be effective in reducing arterial stiffness and improving cardiorespiratory fitness than aerobic training alone.

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Watanabe, T. , Yabumoto, T. , Shin, S. , Shi, B. and Matsuoka, T. (2014) Effect of Short-Term Whole-Body Vibration Training on Metabolic Risk Factors, Inflammatory Markers, and Arterial Stiffness. Advances in Bioscience and Biotechnology, 5, 438-445. doi: 10.4236/abb.2014.55053.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Magliano, D.J., Shaw, J.E. and Zimmet, P.Z. (2006) How to Best Define the Metabolic Syndrome. Annals of Medicine, 38, 34-41. http://dx.doi.org/10.1080/07853890500300311
[2] Alberti, K.G., Eckel, R.H., Grundy, S.M., Zimmet, P.Z., Cleeman, J.I., Donato, K.A., et al. (2009) Harmonizing the Metabolic Syndrome: A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation, 120, 1640-1645.
[3] Eberly, L.E., Prineas, R., Cohen, J.D., Vazquez, G., Zhi, X., Neaton, J.D., et al. (2006) Metabolic Syndrome: Risk Factor Distribution and 18-Year Mortality in the Multiple Risk Factor Intervention Trial. Diabetes Care, 29, 123-130.
[4] Guo, W., Kawano, H., Piao, L., Itoh, N., Node, K. and Sato, T. (2011) Effects of Aerobic Exercise on Lipid Profiles and High Molecular Weight Adiponectin in Japanese Workers. Internal Medicine, 50, 389-395.
[5] Becker-Grunig, T., Klose, H., Ehlken, N., Lichtblau, M., Nagel, C., Fischer, C., et al. (2013) Efficacy of Exercise Training in Pulmonary Arterial Hypertension Associated with Congenital Heart Disease. International Journal of Cardiology, 168, 375-381. http://dx.doi.org/10.1016/j.ijcard.2012.09.036
[6] Braz, N.F., Carneiro, M.V., Oliveira-Ferreira, F., Arrieiro, A.N., Amorim, F.T., Lima, M.M., et al. (2012) Influence of Aerobic Training on Cardiovascular and Metabolic Parameters in Elderly Hypertensive Women. International Journal of Preventive Medicine, 3, 652-659.
[7] Voulgari, C., Pagoni, S., Vinik, A. and Poirier, P. (2013) Exercise Improves Cardiac Autonomic Function in Obesity and Diabetes. Metabolism 62, 609-621. http://dx.doi.org/10.1016/j.metabol.2012.09.005
[8] Vissers, D., Verrijken, A., Mertens, I., Van Gils, C., Van de Sompel, A., Truijen, S., et al. (2010) Effect of Long-Term Whole Body Vibration Training on Visceral Adipose Tissue: A Preliminary Report. Obesity Facts, 3, 93-100.
[9] Behboudi, L., Azarbayjani, M.A., Aghaalinejad, H. and Salavati, M. (2011) Effects of Aerobic Exercise and Whole Body Vibration on Glycaemia Control in Type 2 Diabetic Males. Asian Journal of Sports Medicine, 2, 83-90.
[10] Figueroa, A., Gil, R., Wong, A., Hooshmand, S., Park, S.Y., Vicil, F., et al. (2012) Whole-Body Vibration Training Reduces Arterial Stiffness, Blood Pressure and Sympathovagal Balance in Young Overweight/Obese Women. Hypertension Research, 35, 667-672. http://dx.doi.org/10.1038/hr.2012.15
[11] Pollock, M.L., Wilmore, J.H. and Fox, S.M. (1984) Exercise in Health and Disease: Evaluation and Prescription for Prevention and Rehabilitation. W.B. Saunders, Philadelphia.
[12] Yamashina, A., Tomiyama, H., Takeda, K., Tsuda, H., Arai, T., Hirose, K., et al. (2002) Validity, Reproducibility, and Clinical Significance of Noninvasive Brachial-Ankle Pulse Wave Velocity Measurement. Hypertension Research, 25, 359-364. http://dx.doi.org/10.1291/hypres.25.359
[13] Hirai, T., Sasayama, S., Kawasaki, T. and Yagi, S. (1989) Stiffness of Systemic Arteries in Patients with Myocardial Infarction: A Noninvasive Method to Predict Severity of Coronary Atherosclerosis. Circulation, 80, 78-86.
[14] Lehmann, E.D., Hopkins, K.D., Rawesh, A., Joseph, R.C., Kongola, K., Coppack, S. W., et al. (1998) Relation between Number of Cardiovascular Risk Factors/Events and Noninvasive Doppler Ultrasound Assessments of Aortic Compliance. Hypertension, 32, 565-569.
[15] Miyaki, A., Maeda, S., Choi, Y., Akazawa, N., Tanabe, Y., So, R., et al. (2012) The Addition of Whole-Body Vibration to a Lifestyle Modification on Arterial Stiffness in Overweight and Obese Women. Artery Research, 6, 85-91.
[16] Otsuki, T., Takanami, Y., Aoi, W., Kawai, Y., Ichikawa, H. and Yoshikawa, T. (2008) Arterial Stiffness Acutely Decreases after Whole-Body Vibration in Humans. Acta Physiologica, 194, 189-194.
[17] Lythgo, N., Eser, P., de Groot, P. and Galea, M. (2009) Whole-Body Vibration Dosage Alters Leg Blood Flow. Clinical Physiology and Functional Imaging, 29, 53-59. http://dx.doi.org/10.1111/j.1475-097X.2008.00834.x
[18] Maloney-Hinds, C., Petrofsky, J. S. and Zimmerman, G. (2008) The Effect of 30 Hz vs. 50 Hz Passive Vibration and Duration of Vibration on Skin Blood Flow in the Arm. Medical Science Monitor, 14, CR112-116.
[19] Smiesko, V., Kozik, J. and Dolezel, S. (1985) Role of Endothelium in the Control of Arterial Diameter by Blood Flow. Blood Vessels, 22, 247-251.
[20] Pohl, U., Holtz, J., Busse, R. and Bassenge, E. (1986) Crucial Role of Endothelium in the Vasodilator Response to Increased Flow in Vivo. Hypertension, 8, 37-44.
[21] Joannides, R., Haefeli, W.E., Linder, L., Richard, V., Bakkali, E. H, Thuillez, C., et al. (1995) Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries in Vivo. Circulation, 91, 1314-1319.
[22] Okahara, K., Sun, B. and Kambayashi, J. (1998) Upregulation of Prostacyclin Synthesis-Related Gene Expression by Shear Stress in Vascular Endothelial Cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 18, 1922-1926.
[23] Paoletti, R., Bolego, C., Poli, A. and Cignarella, A. (2006) Metabolic Syndrome, Inflammation and Atherosclerosis. Vascular Health and Risk Management, 2, 145-152.
[24] Ross, R. (1999) Atherosclerosis Is an Inflammatory Disease. American Heart Journal, 138, S419-S420.
[25] Petersen, A.M. and Pedersen, B.K. (2005) The Anti-Inflammatory Effect of Exercise. Journal of Applied Physiology, 98, 1154-1162. http://dx.doi.org/10.1152/japplphysiol.00164.2004
[26] Norata, G.D., Marchesi, P., Pulakazhi Venu, V.K., Pasqualini, F., Anselmo, A., Moalli, F., et al. (2009) Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and Atherosclerosis. Circulation, 120, 699-708.
[27] Wei, M., Gibbons, L.W., Kampert, J.B., Nichaman, M.Z. and Blair, S.N. (2000) Low Cardiorespiratory Fitness and Physical Inactivity as Predictors of Mortality in Men with Type 2 Diabetes. Annals of Internal Medicine, 132, 605-611.
[28] Hu, F.B., Stampfer, M.J., Solomon, C., Liu, S., Colditz, G.A., Speizer, F.E., et al. (2001) Physical Activity and Risk for Cardiovascular Events in Diabetic Women. Annals of Internal Medicine, 134, 96-105.
[29] Church, T.S., Cheng, Y.J., Earnest, C.P., Barlow, C.E., Gibbons, L.W., Priest, E.L., et al. (2004) Exercise Capacity and Body Composition as Predictors of Mortality among Men with Diabetes. Diabetes Care, 27, 83-88.
[30] Hendriksen, I.J. and Meeuwsen, T. (2003) The Effect of Intermittent Training in Hypobaric Hypoxia on Sea-Level Exercise: A Cross-Over Study in Humans. European Journal of Applied Physiology, 88, 396-403.
[31] Kumagai, S., Kai, Y., Nagano, M., Zou, B., Kishimoto, H. and Sasaki, H. (2005) Relative Contributions of Cardiorespiratory Fitness and Visceral Fat to Metabolic Syndrome in Patients with Diabetes Mellitus. Metabolic Syndrome and Related Disorders, 3, 213-220.
[32] Lakka, T.A., Laaksonen, D.E., Lakka, H.M., Mannikko, N., Niskanen, L.K., Rauramaa, R., et al. (2003) Sedentary Lifestyle, Poor Cardiorespiratory Fitness, and the Metabolic Syndrome. Medicine & Science in Sports & Exercise, 35, 1279-1286. http://dx.doi.org/10.1249/01.MSS.0000079076.74931.9A
[33] Rittweger, J., Ehrig, J., Just, K., Mutschelknauss, M., Kirsch, K.A. and Felsenberg, D. (2002) Oxygen Uptake in Whole-Body Vibration Exercise: Influence of Vibration Frequency, Amplitude, and External Load. International Journal of Sports Medicine, 23, 428-432. http://dx.doi.org/10.1055/s-2002-33739
[34] So, R., Etoa, M., Tsujimoto, T. and Tanaka, K. (2013) Acceleration Training for Improvingphysical Fitness and Weight Loss Inobese Women. Obesity Research & Clinical Practice (Epub Ahead of Print).

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