Socioeconomic Indices Performance for HIV Diagnostic on Severely Malnourished Children in Burkina Faso

Léon G. Blaise Savadogo, Philippe Donnen, Michèle Dramaix

CR2-Epidemiology-Biostatistics-Clinical Research, School of Public Health, Université Libre de Bruxelles, Bruxelles, Belgique.
CR3-Politiques et Systèmes de Santé, Santé Internationale, School of Public Health, Université Libre de Bruxelles, Bruxelles, Belgique.
Department of Epidemiology and Public Health, Child and Mother Health, Nutrition and Survival Unit,Institut Supérieur des Sciences de la Santé, Bobo Dioulasso, Burkina Faso;CR2-Epidemiology-Biostatistics-Clinical Research, School of Public Health, Université Libre de Bruxelles, Bruxelles, Belgique.

DOI: 10.4236/wja.2014.41013                

Abstract

Children living with HIV should be diagnosed as early as possible and linked to antiretroviral treatment. The costs of HIV virological testing, individual and social implications of the disease require critical quality of the medical approach to diagnostic strategy. Socioeconomic data can be used to refine the medical decision. The objective of this analysis was to determine informative capacity of socioeconomic indices in the diagnosis and approach of HIV in severely malnourished children using receiver operating characteristic (ROC) curves. Materials and Methods: This was a test performance analysis conducted from data of severely malnourished children at an inpatient feeding therapeutic center in Ouagadougou. Anthropometric and social indices have been used as tests; their sensitivity, specificity and predictive values have been calculated. ROC curves and areas under curves were obtained. Medical decision aid scheme has been validated from severely malnourished children data. Results: Socioeconomic indices showed high performance to discriminate severely malnourished HIV infected and uninfected children, with high area under ROC curves. The medical decision aid scheme specificity reached 97.6% with predictive values close to 85%. Conclusion: This approach can help for expanding ART for children in low income countries and achieve the maximum ART benefits in child socioeconomic kneed context.

Keywords

Socioeconomic Indices; Test Performance; HIV; Severely Malnourished Children

Conflicts of Interest

The authors declare no conflicts of interest.

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