Advanced Primary Lymphoma of Oral Cavity: Report of a Case

Somayeh Alirezaei, Maryam Baharvand, Bita Tavakoli, Soodeh Sarikhani, Ahmad R. Mafi

Department of Oral and Maxillofacial Medicine, Dental School, Islamic Azad University, Tehran, Iran.
Department of Oral and Maxillofacial Medicine, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Oral and Maxillofacial Radiology, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Radiation Oncology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

DOI: 10.4236/ojst.2014.43017                

Abstract

Usually the oral manifestations of NHL are secondary to a more widespread involvement throughout the body, however, it can rarely present as a primary lesion in the oral cavity, having 0.1% - 0.2% prevalence. In this paper we report a case of highly proliferative oral non-Hodgkin lymphoma which presented with very mild symptoms, but had a sudden and significant progression in less than two weeks with involvement of all four quadrants of the oral cavity.

Keywords

Lymphoma; Intra Oral Swelling; Four Quadrant

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Canales, J.O., Vadillo, R., de Faria, P.E., Contreras, S.J., Leite, F.P. and Chaves, M.G. (2011) Systematic Review of Lymphoma in Oral Cavity and Maxillofacial Region. Acta Odontológica Latinoamericana, 24, 245-250.
[2]	Essadi, I., Ismaili, N., Tazi, E., Elmajjaoui, S., Saidi, A., Ichou, M., et al. (2008) Primary Lymphoma of the Head and Neck: Two Case Reports and Review of the Literature. Cases Journal, 1, 426. http://dx.doi.org/10.1186/1757-1626-1-426
[3]	Krol, A.D., le Cessie, S., Snijder, S., Kluin-Nelemans, J.C., Kluin, P.M. and Noordijk, E.M. (2003) Primary Extranodal Non-Hodgkin’s Lymphoma (NHL): The Impact of Alternative Definitions Tested in the Comprehensive Cancer Centre West Population-Based NHL Registry. Annals of Oncology, 14, 131-139. http://dx.doi.org/10.1093/annonc/mdg004
[4]	Ramani, P., Ahmed, S. and Janaki, V.R. (2004) Primary Extranodal Non-Hodgkin’s Lymphoma of the Oral Cavity. Indian Journal of Dermatology, Venereology and Leprology, 70, 172-174.
[5]	Epstein, J.B., Epstein, J.D., Le, N.D. and Gorsky, M. (2001) Characteristics of Oral and Paraoral Malignant Lymphoma: A Population-Based Review of 361 Cases. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 92, 519-525. http://dx.doi.org/10.1067/moe.2001.116062
[6]	Van der Waal, R.I., Huijgens, P.C., van der Valk, P. and van der Waal, I. (2005) Characteristics of 40 Primary Extranodal Non-Hodgkin’s Lymphomas of the Oral Cavity in Perspective of the New WHO Classification and the International Prognostic Index. International Journal of Oral and Maxillofacial Surgery, 34, 391-395. http://dx.doi.org/10.1016/j.ijom.2004.08.009
[7]	Shah, G.H., Panwar, S.K., Chaturvedi, P.P. and Kane, S.N. (2011) Isolated Primary Extranodal Lymphoma of the Oral Cavity: A Series of 15 Cases and Review of Literature from a Tertiary Care Cancer Centre in India. Indian Journal of Medical and Paediatric Oncology, 32, 76-81. http://dx.doi.org/10.4103/0971-5851.89776
[8]	Bhattacharyya, I., Chehal, H.K., Cohen, D.M. and Al-Quran, S.Z. (2010) Primary Diffuse Large B-Cell Lymphoma of the Oral Cavity: Germinal Center Classification. Head and Neck Pathology, 4, 181-191. http://dx.doi.org/10.1007/s12105-010-0184-4
[9]	Jayakrishnan, R., Thomas, G., Kumar, A., Nair, R.A. and Mathews, S. (2011) Non-Hodgkin’s Lymphoma of the Hard Palate. Journal of the Indian Medical Association, 109, 755-756.