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Salivary Duct Carcinoma of the Parotid Gland Definitively Diagnosed by Immunohistochemical Examination of Pulmonary Metastases

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DOI: 10.4236/crcm.2014.33029    2,438 Downloads   3,505 Views   Citations


Salivary duct carcinoma (SDC) is a rare, high-grade, aggressive malignancy, as having a morphologic resemblance to ductal carcinoma of the breast. We present here an atypical SDC of the parotid gland in a 63-year-old man that was diagnosed from immunohistochemical findings. The immunohistochemistry was similar in the parotid lesion and pulmonary metastases in autopsy specimens, but only the latter showed a cribriform pattern and comedolike necrosis. Although the parotid tumor was treated with concurrent chemoradiotherapy and adjuvant chemotherapy for over 21 months, the patient died of respiratory failure caused by advanced pulmonary metastases.

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The authors declare no conflicts of interest.

Cite this paper

Yonemoto, M. , Onizawa, K. , Yamagata, K. , Hasegawa, S. , Yanagawa, T. and Bukawa, H. (2014) Salivary Duct Carcinoma of the Parotid Gland Definitively Diagnosed by Immunohistochemical Examination of Pulmonary Metastases. Case Reports in Clinical Medicine, 3, 118-121. doi: 10.4236/crcm.2014.33029.


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