The Evaluation of the Knee Joint in Terms of Magnetic Resonance Imaging Measurements in Osteoarthritis Patients: A Comparative Study Comprising a Control Group
Bozkurt Gulek, Gokhan Soker, Ertugrul Erken, Yakup Yesilkaya, Behice Durgun, Nazan Alpaslan, Eda Söker, Omer Kaya, Eren Erken
Department of Anatomy, Cukurova University, Adana, Turkey.
Department of Biostatistics, Cukurova University, Adana, Turkey.
Department of Nephrology, Gaziosmanpasa University, Tokat, Turkey.
Department of Physical Therapy and Rehabilitaiton, Numune Teaching and Research Hospital, Adana, Turkey.
Department of Radiology, Kirsehir State Hospital, Kirsehir, Turkey.
Department of Radiology, Namik Kemal University, Tekirdag, Turkey.
Department of Radiology, Numune Teaching and Research Hospital, Adana, Turkey.
Department of Rheumatology and Immunology, Cukurova University, Adana, Turkey.
DOI: 10.4236/ojrad.2014.41014   PDF   HTML     3,250 Downloads   4,593 Views   Citations

Abstract

The aim of this study was to assess the knee joints of osteoarthritis patients in terms of clinical and magnetic resonance imaging (MRI) measurements and draw definitive conclusions from these quantimetric data. In order to achieve the above-mentioned goal, the knees of individuals from two distinct groups were examined by MRI. One group consisted of osteoarthritis patients while the other comprised the control individuals. All individuals from both groups underwent clinical and MRI measurements concerning their knees. These data were compared by using the statistical software from the Statistical Package for Social Sciences (SPSS) v.15 program. Statistically significant differences were found between the control and patients groups in terms of the measurements of the second (short) diameter of the medial femoral condyle, and the intercondylar distance (p < 0.05). In addition to these findings, the Receiver Operating Characteristics (ROC) curve analysis gave statistically significant results for both of these measurements. The cutoff values for these criteria were as follows in sequence order: a sensitivity of 75% and a specificity of 52% for the medial femoral condyle, and a sensitivity of 70% and a specificity of 70% for the intercondylar distance. The ROC curve data may not be a deterministic outcome alone for this study. But it may in fact have a significant meaning when it is evaluated together with other statistically significant data. The t-test for Equality of Means, for example, gave significant results, concerning the measurements of the short axis of the medial femoral condyle and the intercondylar distance. It is well known that it is the medial portion of the knee joint which deteriorates the most during the process of osteoarthritis of the knee (OAK), and this complies with the results of this study.

Share and Cite:

Gulek, B. , Soker, G. , Erken, E. , Yesilkaya, Y. , Durgun, B. , Alpaslan, N. , Söker, E. , Kaya, O. and Erken, E. (2014) The Evaluation of the Knee Joint in Terms of Magnetic Resonance Imaging Measurements in Osteoarthritis Patients: A Comparative Study Comprising a Control Group. Open Journal of Radiology, 4, 111-119. doi: 10.4236/ojrad.2014.41014.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Kirazli, Y. (2011) Current Approach to the Guidelines for the Diagnosis and Treatment of Osteoarthritis. Turkish Journal of Geriatrics, 14, 119-125.
[2] Gudbergsen, H., Boesen, M., Christensen, R., Bartels, E.M., Henriksen, M., Danneskiold-Samsoe, B. and Bliddal, H. (2013) Changes in Bone Marrow Lesions in Response to Weight Loss in Obese Knee Osteoarthritis Patients: A Prospective Cohort Study. BMC Musculoskeletal Disorders, 14, 106. http://dx.doi.org/10.1186/1471-2474-14-106
[3] Neogi, T. (2012) Clinical Significance of Bone Changes in Osteoarthritis. Therapeutic Advances in Musculoskeletal Disease, 4, 259-267. http://dx.doi.org/10.1177/1759720X12437354
[4] Ornetti, P., Laroche, D., Morisst, C., Beis, J.N., Tavernier, C. and Maillefert, J.F. (2011) Three-Dimensional Kinematics of the Lower Limbs in Hip Osteoarthritis during Walking. Journal of Back and Musculoskeletal Rehabilitation, 24, 201-208.
[5] Guccione, A.A., Felson, D.T. and Anderson, J.J. (1990) Defining Arthritis and Measuring Functional Status in Elders: Methodological Issues in the Study of Disease and Physical Disability. American Journal of Public Health, 80, 945949. http://dx.doi.org/10.2105/AJPH.80.8.945
[6] Lawrence, R.C., Felson, D.T., Helmick, C.G., Arnold, L.M., Choi, H., Devo, R.A., et al. (2008) Estimates of the Prevalance of Arthritis and Other Rheumatic Conditions in the United States. Arthritis & Rheumatology, 58, 26-35.
http://dx.doi.org/10.1002/art.23176
[7] Dieppe, P. (2011) Developments in Osteoarthritis. Rheumatology, 50, 245-247.
http://dx.doi.org/10.1093/rheumatology/keq373
[8] Hunter, D.J., Niu, J.B., Zhang, Y., LaValley, M., Mc Lennan, C.E., Hudelmaier, M., Eckstein, F. and Felson, D.T. (2008) Premorbid Knee Osteoarthritis Is Not Characterized by Diffuse Thinness: The Framingham Osteoarthritis Study. Annals of the Rheumatic Diseases, 67, 1545-1549. http://dx.doi.org/10.1136/ard.2007.076810
[9] Bullough, P.G. (2004) The Role of Joint Architecture in the Etiology of Arthritis. Osteoarthritis and Cartilage, 12, 2-9.
http://dx.doi.org/10.1016/j.joca.2003.09.010
[10] Ding, C., Cicuttini, F. and Jones, G. (2008) How Important Is MRI for Detecting Early Osteoarthritis? Nature Clinical Practice Rheumatology, 4, 4-5. http://dx.doi.org/10.1038/ncprheum0676
[11] Dore, D., Quinn, S., Ding, C., Winzenberg, T., Zhai, G., Cicuttini, F. and Jones, G. (2010) Natural History and Clinical Significance of MRI-Detected Bone Marrow Lesions at the Knee: A Prospective Study in Community Dwelling Older Adults. Arthritis Research and Therapy, 12, 223. http://dx.doi.org/10.1186/ar3210
[12] Reichenbach, S., Guermazi, A., Niu, J., Neogi, T., Hunter, D.J., Roemer, F.W., et al. (2008) Prevalance of Bone Attrition on Knee Radiographs and MRI in a Community-Based Cohort. Osteoarthritis and Cartilage, 16, 1005-1010.
http://dx.doi.org/10.1016/j.joca.2008.02.001
[13] Tamez-Pena, J.G., Gonzales, P.C., Screyer, E., Farber, J. and Totterman, S. (2010) Early Detection of Changes in Articular Cartilage Morphology: Data from the Osteoarthritis Initiative. 4th International Workshop on Imaging-Based Measures of Osteoarthritis, Rochester.
[14] Frost, H.M. (1994) Wollf’s Law and Bone’s Structural Adaptations to Mechanical Usage: An Overview for Clinicians. Angle Orthodontist, 64, 175-188.
[15] Goldring, M.B. (2012) Chondrogenesis, Chondrocyte Differentiation, and Articular Cartilage Metabolism in Health and Osteoarthritis. Therapeutic Advances in Musculoskeletal Disease, 4, 269-285.
http://dx.doi.org/10.1177/1759720X12448454
[16] Bullough, P. (1981) Synovial and Osseous Inflammation in Osteoarthritis. Seminars in Arthritis and Rheumatism, 11, 146. http://dx.doi.org/10.1016/0049-0172(81)90083-4
[17] Brandt, K.D. (2010) Defining Osteoarthirits: What It Is and What It Is Not. Journal of Musculoskeletal Medicine, 27, 9.
[18] Bredbenner, T., Eliason, T.D., Potter, R.S., Mason, R.L., Havill, L.M. and Nicolella, D.P. (2010) Statistical Shape Modeling Describes Variation in Tibia and Femur Surface Geometry between Control and Incidence Groups from the Osteoarthritis Initiative Database. Journal of Biomechanics, 43, 1786-1789.
http://dx.doi.org/10.1016/j.jbiomech.2010.02.015
[19] Cooke, D., Scudamore, A., Li, J., Wyss, U., Bryant, T. and Costigan, P. (1997) Axial Lower-Limb Alignment: Comparison of Knee Geometry in Normal Volunteers and Osteoarthritis Patients. Osteoarthritis and Cartilage, 5, 39-47.
http://dx.doi.org/10.1016/S1063-4584(97)80030-1
[20] Baert, I.A.C., Staes, F., Truijen, S., Mahmoudian, A., Noppe, N., Vanderscueren, G., et al. (2013) Weak Associations between Structural Changes on MRI and Symptoms, Function, and Muscle Strength in Relation to Knee Osteoarthritis. Knee Surgery, Sports Traumatology, Arhroscopy.
[21] Phillips, M.D. and Pomeranz, S.J. (2009) Knee Osteoarthritis: MRI in the Landscape of Current and Potential Treatment. WorldCare Clinical, 3.
[22] Hernandez-Molina, G., Neogi, T., Hunter, D.J., Niu, J., Guermazi, A., Reichenbach, S., et al. (2008) The Association of Bone Attrition with Knee Pain and Other MRI Features of Osteoarthritis. Annals of the Rheumatic Diseases, 67, 43-47. http://dx.doi.org/10.1136/ard.2007.070565
[23] Yusuf, E., Kortekaas, M.C., Watt, I., Huizinga, T.W.J. and Kloppenburg, M. (2011) Do Knee Abnormalilities Visualized on MRI Explain Knee Pain in Knee Osteoarthritis? A Systematic Review. Annals of the Rheumatic Diseases, 70, 60-67. http://dx.doi.org/10.1136/ard.2010.131904

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.