Time-resolved laser flash photolysis study on transient reaction between excited triplet state of anthraquinone derivatives (AQS) and 2-deoxythymidine

Abstract

The transient absorption spectra and kinetics of excited triplet state of anthraquinone derivatives 2-anthraquinonesulfonatesodium (AQS) and 2-deoxythymidine (dT) have been investigated in CH3CN-H2O (97:3) using the time-resolved laser flash photolysis technique (KrF, 248 nm). The absorption spectra of dT radical cation and the radical anion of AQS have been observed. From dynamic and thermodyrnamic analysis, the mechanism of this transient reaction has been initially analysed.

Share and Cite:

Ma, J. (2014) Time-resolved laser flash photolysis study on transient reaction between excited triplet state of anthraquinone derivatives (AQS) and 2-deoxythymidine. Natural Science, 6, 1-4. doi: 10.4236/ns.2014.61001.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Zhang, S.M., Han, S.T. and Liu, Y.H. (2004) Progress of study on photonuclease-anthraquinone derivatives. Journal Hebei Normal University, 3, 27-30.
[2] David, T., Breslin, D.T., Coury, J.R., et al. (1997) Anthrquinone photonuclease structure determines its mode of binding to DNA and the cleavage chemistry observed. Journal of America Chemistry Society, 119, 5043-5045.
http://dx.doi.org/10.1021/ja963607h
[3] Ma, J.H., Lin, W.Z., Wang, W.F., Han, Z.H., Yao, S.D. and Lin, N.Y. (1999) Characterization of reactive intermediates in laser photolysis of nucleoside using sodium salt of 9,10-anthrax-quinone-2-sulfonate as photosensitizer. Radiation Physics and Chemistry, 54, 337-340.
http://dx.doi.org/10.1016/S0969-806X(98)00300-4
[4] Loeff, A., Treinin, H. and Linsckitz H. (1983) Photochemistry of 9,10-anthraquinone-2-sulfonate in solution. 1. Intermediates and mechanism. Journal of Physics and Chemistry, 87, 2536-2540.
http://dx.doi.org/10.1021/j100237a017
[5] Loeff, J., Rabani, A., Treinin, H. and Linschitz H. (1993) Charge transfer and reactivity of n&π* and ππ * organic triplets, including anthraquinonesulfonates, in interactions with inorganic anion: A comparative study based on classical Marcus theory. Journal of America Chemistry Society, 115, 8933-8937.
http://dx.doi.org/10.1021/ja00073a007
[6] Ma, J.H., Lin, W.Z., Wang, W.F., Han, Z.H., Yao, S.D. and Lin, N.Y. (2002) Laser photolysis of interaction of poly-guanylic acid (5’) with anthraquinone-2-sulfonate. Science in China, 45, 384-387.
[7] Candeias, L.P. and Steenken, S. (1993) Electron transfer in di(deoxy)nucleoside phosphates in aqueous solution: Rapid migration of oxidation damage (via adenine) to guanine. Journal of America Chemistry Society, 115, 24372441. http://dx.doi.org/10.1021/ja00059a044
[8] Ma, J.H., Lin, W.Z., Han, Z.H., Yao, S.D. and Lin, N.Y. (2006) Electron transfer reaction between desoxyadenosine and triplet 2-methyl-1,4-naphthaquinone: A laser photolysis study. Chemistry Research Chinese University, 22, 397-341.
http://dx.doi.org/10.1016/S1005-9040(06)60126-8
[9] Rehm, D. and Weller, D. (1970) Kinetics of fluorescence quenching by electron and hydrogen-atom transfer. Israel Journal of Chemistry, 8, 259-262.
http://dx.doi.org/10.1002/ijch.197000029
[10] Miller, L.L., Nordblum, G.B. and Mayeda, E.A. (1972) A simple comprehensive correlation of organic oxiation and ionization potentials. Journal of Organic Chemistry, 37, 916-919. http://dx.doi.org/10.1021/jo00971a023
[11] Nikogosyan, D.N. (1990) Two-quantum UV photochemistry of nucleic acids: Comparison with conventional lowintensity UV photochemistry and radiation chemistry. International Journal of Radiation Biology, 57, 233-236.
http://dx.doi.org/10.1080/09553009014552411
[12] Colson, A.O., Beslter, B., Close, D.M. and Sevilla, M.D. (1992) Ab initio molecular orbital calcuiations of DNA bases and their radical ions in various protonation states: Evidence for proton transfer in GC base pair radical anions. Journal of Physical Chemistry, 96, 661-668.
http://dx.doi.org/10.1021/j100181a028
[13] Loeff, I., Rabani, J. and Linschitz, H. (1993) Charge transfer and reactivity of nπ* and ππ* organic triplets, including anthraquinonesulfonates, in interactions with inorganic anion: A comparative study based on classical Marcus theory. Journal of America Chemistry Society, 115, 8933-8942. http://dx.doi.org/10.1021/ja00073a007
[14] Fox, M.A. and Chanon, M. (1988) Photoinduced electron transfer. Elsevier, Amsterdam, 48-192.
http://library.wur.nl/WebQuery/clc/512801

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.