Patient Safety: An Injectable Education

Arnold William Klein

Geffen School of Medicine, University of California, Los Angeles, USA.

DOI: 10.4236/jcdsa.2013.33A2009                

Abstract

Until recently, the effects of all injectable filling agents were temporary and very rarely associated with permanent problems. In the past, the permanent injectable silicone had been used but had been so problematic that the Justice Department filed injunctions against certain physicians on behalf of the FDA. After 2000 a dangerous pattern grew in the corridors of Washington DC, where politics and money changed the face of America and the field of aesthetics to the detriment of the faces of the consumers. Industry has accomplished the approval of synthetic agents that should have never reached the market. Once injected under skin, the body cannot digest these agents and the immune system walls them off with resultant formation of nodules, which at times require surgical removal.

Keywords

Fillers; Sculptra; Artefill; Artecoll; Safety; Injectables

Conflicts of Interest

The authors declare no conflicts of interest.

References

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[3]	A. W. Klein, “Reluctant to Use Artecoll: Letter to the Editor,” Skin & Allergy News, Rockville, 2002, p. 16.
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[8]	J. Alijotas-Reig, V. Garcia-Gimenez and M. Vilardell-Tarres, “Late-Onset Immune-Mediated Adverse Effects after Poly-L-Lactic Acid Injection in Non-HIV Patients: Clinical Findings and Long-Term Follow-Up,” Dermatology, Vol. 219, No. 4, 2009, pp. 303-308. http://dx.doi.org/10.1159/000243804
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[12]	Apr 23, 2012—Dear Dr. Klein Disaster: I Was Injected Sculptra First Time in May 2009 (3 Series) in Cheek Hollows, Temples and Neck. I Had Excelent Subtle Results, ...What Do About Sculptra (NewFill) Lumps and Granulomas Doctor... www.realself.com/review/the-whole-truth-please
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