C1-C2 Pott’s Disease, a Rare Location of Spine Tuberculosis


The authors report a new case of spine tuberculosis of C1-C2 occurred in a 58-year-old negative HIV patient that was responsible of inflammatory cervical pain with multidirectional stiffness and complicated by spastic quadriplegia. The diagnosis was made on the basis of presumptive elements, including cervical spinal CT scan, which showed atlan-to-axial subluxation (C1-C2) with destruction of the odontoid apophysis and lateral mass of the atlas and favorable evolution under specific antibiotic treatment with ethambutol, isoniazid, rifampicin, pyrazinamide and immobilization with brace cast, despite the absence of bacteriological and anatomo-pathological evidence of certainty. The evolution has been favorable, with the disappearance of cervical pain, progressive motor recovery and resumption of autonomy of walking.

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H. Ntsiba, N. N’Soundhat and D. Kidédé, "C1-C2 Pott’s Disease, a Rare Location of Spine Tuberculosis," Open Journal of Rheumatology and Autoimmune Diseases, Vol. 3 No. 4, 2013, pp. 224-226. doi: 10.4236/ojra.2013.34035.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] A. Mehrotra, K. K. Das, A. P. Nair, R. Kumar, A. K. Srivastava, R. N. Sahu and R. Kumar, “Pediatric Cranio-Vertebral Junction Tuberculosis: Management and Outcome,” Child’s Nervous System, Vol. 29, No. 5, 2013, pp. 809-814. http://dx.doi.org/10.1007/s00381-012-1980-9
[2] K. Chaudhary, P. Potdar, M. Bapat, A. Mathod and V. Laheri, “Structural Odontoid Lesions in Craniovertebral Tuberculosis: A Review of 15 Cases,” Spine, Vol. 37, No. 14, 2012, pp. 836-843. http://dx.doi.org/10.1097/BRS.0b013e31824a4c8f
[3] I. K. Dhammi, S. Singh and A. K. Jain, “Hemiplegic/Monoplegic Presentation of Cervical Spine C1-C2 Tuberculosis,” European Spine Journal, Vol. 10, No. 6, 2001, pp. 540-544.
[4] H. Ebadi and D. Fathi, “Unilateral Hypoglossal Nerve Palsy: As the Only Presentation of Tuberculosis,” Acta Medica Iranica, Vol. 50, No. 10, 2012, pp. 717-720.
[5] F. Marino-Sanchez, E. Rioja, M. Rusiecka and I. Alobid, “Cervical Vertebral Tuberculosis Simulating a Pertonsillar Abscess,” Acta Otorrinolaringológica Espanola, Vol. 62, No. 5, 2011, pp. 398-400. http://dx.doi.org/10.1016/j.otorri.2010.07.007
[6] A. K. Jain, S. Kumar and S. M. Tuli, “Tuberculosis of Spine (C1 to D4),” Spinal Cord, Vol. 37, No. 5, 1999, pp. 362-369. http://dx.doi.org/10.1038/sj.sc.3100833
[7] E. Belanger and A. D. Levi, “Tuberculosis of the Axis in a Patient with Systemic Sarcoidosis: Technique of Posterior Open Biopsy of the Dens: Case Report,” Neurosurgery, Vol. 47, No. 4, 2000, pp. 969-972. http://dx.doi.org/10.1097/00006123-200010000-00036
[8] W. Tabib, S. Sayegh, F. Colona d’Istria and M. Mayer, “Atlanto-Axial Pott’s Disease. A Propos of a Case with Review of the Literature,” Chirurgie Orthopedique et Reparatrice de L’appareil Moteur’s, Vol. 80, No. 8, 1994, pp. 734-738.
[9] S. Govender, A. Ramnarain and S. Danaviah, “Cervical Spine Tuberculosis in Children,” Clinical Orthopaedics and Related Research, Vol. 460, 2007, pp. 78-85.
[10] P. Suchomel, J. Stulik, Z. Klézl, J. Chrobok, R. Lukàs, M. Krbec and F. Magerl, “Transarticular Fixation of C1-C2: A Multicenter Retrospective Study,” Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca, Vol. 71, No. 1, 2004, pp. 6-12.
[11] R. Bahadur, T. Goyal, S. S. Dhart and S. K. Tripathy, “Transarticular Screw Fixation for Atlantoaxial Instability-Modified Magerl’s Technique in 38 Patients,” Journal of Orthopaedic Surgery and Research, Vol. 5, No. 87, 2010, p. 8.
[12] R. Mihir, J. Rapat Vinod, N. S. Lahiri, S. Harhavardhan Umesh, K. Mektar, C. Shitij and Chaudhary, “Role of Transarticular Screw Fixation in Tuberculous Atlanto-Axial Instability,” European Spine Journal, Vol. 16, No. 2, 2007, pp. 187-197.
[13] E. Eti, J. C. Daboiko, K. F. Brou, B. Ouali, B. Ouattara, K. D. Koffi and N. M. Kouakou, “Spinal Tuberculosis: Our Experience from a Study of 147 Cases in the Rheumatology Department of the University Hospital of Cocody (Abidjan, Ivory Coast),” Médecine d’Afrique Noire, Vol. 57, No. 5, 2010, pp. 287-292.

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