Successful Treatment of Spine Fracture for Diffuse Idiopathic Skeletal Hyperostosis with Teriparatide—A Report of Two Cases


We experienced 2 cases of spinal fracture in patients aged 80 years or older with diffuse idiopathic skeletal hyperostosis (DISH). Since they decided not to undergo surgical treatment, we provided conservative treatment with teriparatide. There has been no previous study on teriparatide for spine fracture in DISH. This is the first report of the successful use of teriparatide to treat spine fracture in DISH without surgical intervention. Our patients were treated with teriparatide for 8-9 months after diagnosis of the fracture. Union was obtained in two cases and no adverse events were observed during treatment. Our report showed that teriparatide could be an alternative to conventional intervention in spinal fracture of DISH.

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Y. Iida, H. Takahashi, Y. Yokoyama, Y. Inoue, D. Suzuki, K. Hasegawa, S. Tsuge, W. Shishikura, K. Fukutake, R. Takamatsu, K. Nakamura, M. Sekiguchi and A. Wada, "Successful Treatment of Spine Fracture for Diffuse Idiopathic Skeletal Hyperostosis with Teriparatide—A Report of Two Cases," Open Journal of Orthopedics, Vol. 3 No. 6, 2013, pp. 278-282. doi: 10.4236/ojo.2013.36051.

Conflicts of Interest

The authors declare no conflicts of interest.


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