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Enhanced Disinfection Effect of a Compound Disinfectant against Bovine Herpes Virus Type 1 at Low Temperature

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DOI: 10.4236/ojvm.2013.35039    3,356 Downloads   5,305 Views  

ABSTRACT

A compound disinfectant, which consisted of didecyldimethylammonium chloride (DDAC), ortho-dichlorobenzene (1,2-dichlorobenzene, ODB), and chlorocresol (4-chloro-3-methylphenol, CC), and its component chemicals were individually tested for effectiveness against bovine herpes virus type 1 (BHV-1). DDAC, DDAC+ODB, DDAC+CC, and DDAC+ODB+CC showed effectiveness against BHV-1 at room temperature. However, ODB, CC, and ODB+CC showed no virucidal effects. The effects of all disinfectants tested were decreased at low temperature. DDAC showed disinfectant effects at a dilution of 1/800 and DDAC+ODB, DDAC+CC, and DDAC+ODB+CC at dilutions of 1/800 and 1/1600 at low temperature in the presence of 2% fetal bovine serum (FBS) but ODB, CC, and ODB+CC showed no virucidal effects. At low temperature and in the presence of 10% FBS, DDAC, DDAC+ODB, and DDAC+CC showed disinfectant effects at dilutions of 1/800, whereas ODB, CC, and ODB+CC showed no virucidal effects. DDAC+ ODB+CC was more effective (at 1/800 and 1/1600) than the other disinfectants under these conditions. In conclusion, a combination of three disinfectant components (DDAC+ODB+CC), enhanced the disinfectant effects at low temperature and in organic matter contamination.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

M. Nagai, R. Kamimura, R. Seki, T. Shimoyama, T. Kubota and J. Shirai, "Enhanced Disinfection Effect of a Compound Disinfectant against Bovine Herpes Virus Type 1 at Low Temperature," Open Journal of Veterinary Medicine, Vol. 3 No. 5, 2013, pp. 247-251. doi: 10.4236/ojvm.2013.35039.

References

[1] A. G. Grow, “Writing Guidelines to Require Disinfection,” Revue Scientifique et Technique, Vol. 14, No. 2, 1995, pp. 469-477.
[2] D. J. Jefferey, “Chemicals Used as Disinfectants: Active Ingredients and Enhancing Additives,” Revue Scientifique et Technique, Vol. 14, No. 1, 1995, pp. 57-74.
[3] J. Shirai, “Disinfection against the Outbreaks of Foot and Mouth Disease (FMD),” Journal of Disaster Research, Vol. 7, No. 3, 2012, pp. 264-273.
[4] G. Bruins and J. A. Dyer, “Environmental Considerations of Disinfectants Used in Agriculture,” Revue Scientifique et Technique, Vol. 14, No. 2, 1995, pp. 81-94.
[5] G. McDonnell and A. D. Russell, “Antiseptics and Disinfectants: Activity, Action, and Resistance,” Clinical Microbiology Reviews, Vol. 12, No. 1, 1999, pp. 147-179.
[6] P. Maris, “Modes of Action of Disinfectants,” Revue Scientifique et Technique, Vol. 14, No. 1, 1995, pp. 47-55.
[7] R. F. Kahrs, “General Disinfection Guidelines,” Revue Scientifique et Technique, Vol. 14, No. 1, 1995, pp. 105-122.
[8] J. Shirai, T. Kanno, T. Inoue, S. Mitsubayashi and R. Seki, “Effects of Quaternary Ammonium Compounds with 0.1% Sodium Hydroxide on Swine Vesicular Disease Virus,” The Journal of Veterinary Medical Science, Vol. 59, No. 5, 1997, pp. 323-328. doi:10.1292/jvms.59.323
[9] Y. Sakoda, R. Seki and H. Kida, “Effects of Disinfectants against Avian Influenza Virus,” The Japanese Journal of Animal Hygiene, Vol. 32, No. 2, 2006, pp. 67-70 (in Japanese).
[10] Y. Sakoda, Y. Yoshimi, S. Kurokawa and H. Kida, “Effects of Disinfectants against Avian Influenza Viruses,” Journal of the Japan Veterinary Medical Association, Vol. 60, No. 7, 2007, pp. 519-522 (in Japanese).
[11] J. Shirai, T. Kanno, Y. Tsuchiya, S. Mitsubayashi and R. Seki, “Effects of Chlorine, Iodine, and Quaternary Ammonium Compound Disinfectants on Several Exotic Disease viruses,” The Journal of Veterinary Medical Science, Vol. 62, No. 1, 2000, pp. 85-92. doi:10.1292/jvms.62.85
[12] J. Shirai, R. Seki, R. Kamimura and S. Mitsubayashi, “Effects of Invert Soap with 0.05% Sodium Hydroxide on Infectious Bursal Disease Virus,” Avian Disease, Vol. 38, No. 2, 1994, pp. 240-243. doi:10.2307/1591943
[13] Z. G. Kassaify, R. G. E. Hakim, E. G. Rayya, H. A. Shaib and E. K. Barbour, “Preliminary Study on the Efficacy and Safety of Eight Individual and Blended Disinfectants against Poultry and Dairy Indicator Organisms,” Veteriaria Italiana, Vol. 43, No. 4, 2007, pp. 821-830.

  
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