[1]
|
American Cancer Society, “Cancer Facts and Figures, 2012,” 2012.
http://www.cancer.org/acs/ groups/content/@epidemio logysurveilance/docume nts/document/acspc-031941.pdf
|
[2]
|
A. Argiris, M. V. Karamouzis, D. Raben and R. L. Ferris, “Head and Neck Cancer,” Lancet, Vol. 371, No. 9625, 2008, pp. 1695-1709.
doi:10.1016/S0140-6736(08)60728-X
|
[3]
|
B. Ogretmen and Y. A. Hannun, “Biologically Active Sphingolipids in Cancer Pathogenesis and Treatment,” Nature Reviews Molecular Cell Biology, Vol. 4, No. 8, 2004, pp. 604-616. doi:10.1 038/nrc1411
|
[4]
|
Y. A. Hannun and L. M. Obeid, “Principles of Bioactive Lipid Signalling: Lessons from Sphingolipids,” Nature Reviews Molecular Cell Biology, Vol. 9, No. 2, 2008, pp. 139-150. doi:10.1038/nrm2329
|
[5]
|
S. Spiegel and S. Milstien, “Sphingosine-1-Phosphate: An Enigmatic Signalling Lipid,” Nature Reviews Molecular Cell Biology, Vol. 4, No. 5, 2003, pp. 397-407.
doi:10.1038/nrm1103
|
[6]
|
O. H. Lee, Y. M. Kim, Y. M. Lee, et al., “Sphingosine 1-Phosphate Induces Angiogenesis: Its Angiogenic Action and Signaling Mechanism in Human Umbilical Vein Endothelial Cells,” Biochemical and Biophysical Research Communications, Vol. 264, No. 3, 1999, pp. 743-750.
doi:10.1006/b brc.1999.1586
|
[7]
|
N. Bergelin, T. Blom, J. Heikkila, et al., “Sphingosine Kinase as an Oncogene: Autocrine Sphingosine 1-Phosphate Modulates ML-1 Thyroid Carcinoma Cell Migration by a Mechanism Dependent on Protein Kinase CAlpha and ERK1/2,” Endocrinology, Vol. 150, No. 5, 2009, pp. 2055-2063. doi:10.1210/en.2008-0625
|
[8]
|
D. Wang, Z. Zhao, A. Caperell-Grant, et al., “S1P Differentially Regulates Migration of Human Ovarian Cancer and Human Ovarian Surface Epithelial Cells,” Molecular Cancer Therapeutics, Vol. 7, No. 7, 2008, pp. 1993-2002. doi:10.1158/1535-7163.MCT-08-0088
|
[9]
|
L. Wang and S. M. Dudek, “Regulation of Vascular Permeability by Sphingosine 1-Phosphate,” Microvascular Research, Vol. 77, No. 1, 2009, pp. 39-45.
doi:10.1016/j.mvr.2008.09.005
|
[10]
|
O. Cuvillier, G. Pirianov, B. Kleuser, et al., “Suppression of Ceramide-Mediated Programmed Cell Death by Sphingosine-1-Phosphate,” Nature, Vol. 381, No. 6585, 1996, pp. 800-803. doi:10.1038/381800a0
|
[11]
|
T. Kohama, A. Olivera, L. Edsall, et al., “Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase,” Journal of Biological Chemistry, Vol. 273, 1998, pp. 23722-23728. doi:10.1074/jbc.273.37.23722
|
[12]
|
S. M. Mandala, R. Thornton, Z. Tu, et al., “Sphingoid Base 1-Phosphate Phosphatase: A Key Regulator of Sphingolipid Metabolism and Stress Response,” Proceedings of the National Academy of Sciences of USA, Vol. 95, No. 1, 1998, pp. 150-155. doi:10.1073/pnas.95.1.150
|
[13]
|
A. Olivera, T. Kohama, L. Edsall, et al., “Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival,” Journal of Cell Biology, Vol. 147, No. 3, 1999, pp. 545-558. doi:10.1083/jcb.147.3.545
|
[14]
|
S. Spiegel and S. Milstien, “Functions of the Multifaceted Family of Sphingosine Kinases and Some Close Relatives,” Journal of Biological Chemistry, Vol. 282, No. 4, 2007, pp. 2125-2129. doi:10.1074/jbc.R600028200
|
[15]
|
T. Kawamori, T. Kaneshiro, M. Okumura, et al., “Role for Sphingosine Kinase 1 in Colon Carcinogenesis,” FASEB Journal, Vol. 23, No. 2, 2009, pp. 405-414.
doi:10.1096/fj.08-117572
|
[16]
|
J. R. Van Brocklyn, C. A. Jackson, D. K. Pearl, M. S. Kotur, P. J. Snyder and T. W. Prior, “Sphingosine Kinase-1 Expression Correlates with Poor Survival of Patients with Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines,” Journal of Neuropathology & Experimental Neurology, Vol. 64, No. 8, 2005, pp. 695-705.
doi:10.1097/01.jn en.0000175329.59092.2c
|
[17]
|
M. Vadas, P. Xia, G. McCaughan and J. Gamble, “The Role of Sphingosine Kinase 1 in Cancer: Oncogene or Non-Oncogene Addiction?” Biochimica et Biophysica Acta, Vol. 1781, No. 9, 2008, pp. 442-447.
|
[18]
|
U. K. Sinha, V. J. Schorn, C. Hochstim, S. B. Chinn, S. Zhu and R. Masood, “Increased Radiation Sensitivity of Head and Neck Squamous Cell Carcinoma with Sphingosine Kinase 1 Inhibition,” Head & Neck, Vol. 33, No. 2, 2010, pp. 178-188.
|
[19]
|
R. Kolesnick and Z. Fuks, “Radiation and CeramideInduced Apoptosis,” Oncogene, Vol. 22, No. 37, 2003, pp. 5897-5906. doi:10.1038/sj.onc.1206702
|
[20]
|
X. Deng, X. Yin, R. Allan, et al., “Ceramide Biogenesis Is Required for Radiation-Induced Apoptosis in the Germ Line of C. elegans,” Science, Vol. 322, No. 5898, 2008, pp. 110-115. doi:10.1126/sc ience.1158111
|
[21]
|
V. E. Nava, O. Cuvillier, L. C. Edsall, et al., “Sphingosine Enhances Apoptosis of Radiation-Resistant Prostate Cancer Cells,” Cancer Research, Vol. 60, No. 16, 2000, pp. 4468-4474.
|
[22]
|
T. A. Taha, W. Osta, L. Kozhaya, et al., “Down-Regulation of Sphingosine Kinase-1 by DNA Damage: Dependence on Proteases and p53,” The Journal of Biological Chemistry, Vol. 279, No. 19, 2004, pp. 20546-20554.
doi:10.1074/jbc.M401259200
|
[23]
|
A. E. Mahdy, J. C. Cheng, J. Li, et al., “Acid Ceramidase Upregulation in Prostate Cancer Cells Confers Resistance to Radiation: AC Inhibition, a Potential Radiosensitizer,” Molecular Therapy, Vol. 17, No. 3, 2009, pp. 430-438.
doi:10.1038/mt.2008.281
|
[24]
|
K. Shirai, T. Kaneshiro, M. Wada, et al., “A Role of Sphingosine Kinase 1 in Head and Neck Carcinogenesis,” Cancer Prevention Research, Vol. 4, No. 3, 2011, pp. 454-462. doi:10.1158/1940-6207.CAPR-10-0299
|
[25]
|
R. Masood, I. Roy, S. Zu, et al., “Gold Nanorod-Sphingosine Kinase siRNA Nanocomplexes: A Novel Therapeutic Tool for Potent Radiosensitization of Head and Neck Cancer,” Integrative Biology, Vol. 4, No. 2, 2012, pp. 132-141. doi:10.1039/c1ib00060h
|
[26]
|
F. Farshadpour, H. Kranenborg, E. V. Caikoen, et al., “Survival Analysis of Head and Neck Squamous Cell Carcinoma: Influence of Smoking and Drinking,” Head & Neck, Vol. 33, No. 6, 2011, pp. 817-823.
doi:10.1002/hed.21549
|
[27]
|
E. M. Sturgis, “The International Head and Neck Cancer Epidemiology Consortium,” Head & Neck, Vol. 33, No. 1, 2011, p. 141. doi:10.1002/hed.21670
|
[28]
|
M. M. Facchinetti, N. A. Gandini, M. E. Fermento, et al., “The Expression of Sphingosine Kinase-1 in Head and Neck Carcinoma,” Cells Tissues Organs, Vol. 192, No. 5, 2010, pp. 314-324. doi:10.1159/000318173
|
[29]
|
E. Ruckh?berle, A. Rody, K. Engels, et al., “Microarray Analysis of Altered Sphingolipid Metabolism Reveals Prognostic Significance of Sphingosine Kinase 1 in Breast Cancer,” Breast Cancer Research and Treatment, Vol. 112, No. 1, 2007, pp. 41-52.
doi:10.1007/s10549-007-9836-9
|