An evaluation of the arterial occlusions in peripheral arterial disease by 64-detector multi-slice CT angiography: DSA correlation


Objective: Evaluation of peripheral arterial disease with 64-detector multi-slice CT angiography (MDCT- A) and comparison of the results with the results of digital subtraction angiography (DSA), a standard reference. Materials and Method: The written informed consent of the patients and ethics committee approval were obtained. The retrospective study group consisted of 28 patients with a diagnosis of peripheral arterial disease. Using 64-MDCT-A, the arterial tree of the lower extremity was evaluated for the presence of steno-occlusive lesions that might have led to luminal stenosis. The diagnostic reliability of 64-MDCT- A was calculated and compared with that of DSA. Findings: In the segment-based analysis, the sensitivity, specificity, and reliability rates of 64-MDCT angiography in determining significant stenoses were 97.7%, 97%, and 97.3%, respectively. The Kappa co-efficiency for compatibility between 64-MDCT-A and DSA methods in grading stenosis was calculated as 0.896 (P < 0.001) and it was statistically significant. Conclusion: 64-MDCT angiography is significantly compatible with DSA method in the evaluation of peripheral arterial diseases. It is a non-invasive method and can be an alternative to DSA.

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Oztekin, P. , Sonmez, A. , Kucukay, F. , Oztuna, D. , Sanlıdilek, U. and Kosar, U. (2013) An evaluation of the arterial occlusions in peripheral arterial disease by 64-detector multi-slice CT angiography: DSA correlation. World Journal of Cardiovascular Diseases, 3, 250-256. doi: 10.4236/wjcd.2013.32039.

Conflicts of Interest

The authors declare no conflicts of interest.


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