Aggressive Angiomyxoma: An Unusual Female Pelvic Tumour. Report of Three Cases and Review of the Literature

Abstract

Aggressive angiomyxoma was first described in 1983 by Steeper and Rosai, and fewer than 150 cases have been reported in the world medical literature. It is a soft-tissue tumour of the pelvis and perineum. The recurrence rate is high, and often extensive resections are performed with considerable morbidity. These tumours are benign, locally infiltrative mesenchymal neoplasms with a predilection for the female pelvis and perineum and they usually tend to recur. Furthermore, these tumours often reach too large dimensions before becoming clinically symptomatic; their incidence is higher in women of the reproductive age group; however a few cases of its occurrence outside the pelvis have also been reported. In this study, we reported three cases with aggressive pelvic angiomyxoma treated with surgical methods and used an approach that described by Kraske in order to get access to lower rectal cancers. Accurate preoperative diagnosis should alert the surgeon to the need for wide excision, which is essential for prevention of local recurrence.

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J. Martín-Cartes, M. Bustos-Jiménez, M. Tamayo-López, M. Palacios-González, V. Vaca and A. Ortega, "Aggressive Angiomyxoma: An Unusual Female Pelvic Tumour. Report of Three Cases and Review of the Literature," Surgical Science, Vol. 1 No. 2, 2010, pp. 40-45. doi: 10.4236/ss.2010.12008.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] I. J. M. Han-Geurts, A. N. van Geel, L. van Doorn, et al., “Aggressive Angiomyxoma: Multimodality Treatments can Avoid Mutilating Surgery,” European Journal of Surgical Oncology, Vol. 32, No. 10, 2006, pp. 1217-1221.
[2] T. A. Steeper and J. Rosai, “Aggressive Angiomyxoma of the Female Pelvis and Perineum: Report of Nine Cases of a Distinctive Type of Gynaecologic Soft-Tissue Neoplasm,” American Journal of Surgical Pathology, Vol. 7, No. 5, 1983, pp. 463-475.
[3] K. A. Behranwala and J. M. Thomas, “Aggressive’ Angiomyxoma: A Distinct Clinical Entity,” European Journal of Surgical Oncology, Vol. 29, No. 7, 2003, pp. 559- 563.
[4] A. Mathieson, S. Chandrakanth, G. Yousef, et al., “Aggressive Angiomyxoma of the Pelvis: A Case Report,” Canadian Journal of Surgery, Vol. 50, No. 2, 2007, pp. 228-229.
[5] P. M. Magtibay, Z. Salmon, G. L. Keeney, et al., “Aggressive Angiomyxoma of the Female Pelvis and Perineum: A Case Series,” International Journal of Gynecological Cancer, Vol. 16, No. 1, 2006, pp. 396-401.
[6] K. Haldar, I. E. Martinek and S. Kehoe, “Aggressive Angiomyxoma: A Case Series and Literature Review,” European Journal of Surgical Oncology, Vol. 36, No. 4, 2010, pp. 335-339.
[7] S. Dove, P. Remoue, E. Fondrinier, et al., “Unusual Female Pelvic Tumour: Aggressive Angiomyxoma,” European Journal of Obstetrics & Gynecology and Reproductive Biology, Vol. 137, No. 3, 2008, pp. 123-125.
[8] E. L. Nava Flores, M. A. Alvarez Blanco, J. Figueroa Vadillo, et al., “Aggressive Angiomyxoma of the Vulva. Case Report and Literature Review,” Ginecologia Y Obstetricia de Mexico, Vol. 77, No. 7, 2009, pp. 487-490.
[9] A. Wiser, J. Korach, W. H. Gotlieb, E. Fridman, et al., “Importance of Accurate Preoperative Diagnosis in the Management of Aggressive Angiomyxoma: Report of Three Cases and Review of the Literature,” Abdominal Imaging, Vol. 31, No. 3, 2006, pp. 383-386.
[10] H. Adwan, P. D. Kamel and G. Glazer, “A Solitary Encapsulated Pelvic Aggressive Angiomyxoma,” Annals of The Royal College of Surgeons of England, Vol. 86, No. 6, November 2004, pp. W1-W3.
[11] M. Suleiman, C. Duc, S. Ritz and S. Bieri, “Excision of large Aggressive Angiomyxoma in a Woman: Irradiation for Recurrent Disease,” International Journal of Gynecological Cancer, Vol. 16, No. (Suppl. 1), 2006, pp. 356- 360.
[12] M. Onaitis, K. Ludwig, A. Perez-Tamayo, et al., “The Kraske Procedure: A Critical Analysis of a Surgical Approach for Mid-Rectal Lesions,” Journal of Surgical Oncology, Vol. 94, No. 3, 2006, pp. 194-202.
[13] P. Gervaz, O. Huber, P. Buche, et al., “Trans-Sacral (Kraske) Approach for Gastrointestinal Stromal Tumour of the Lower Rectum: Old Procedure for a New Disease,” Colorectal Disease, Vol. 10, No. 9, 2008, pp. 951-952.
[14] S. E. Wilson and H. E. Gordon, “Excision of Rectal Lesions by the Kraske Approach,” American Journal of Surgery, Vol. 118, No. 2, 1969, pp. 213-217.
[15] J. P. Arnaud, M. R. Eloy, G. Clendinnen, et al., “The Posterior Approach for Villous Tumors of the Rectum,” American Journal of Surgery, Vol. 136, No. 2, 1978, pp. 273-275.
[16] J. Christiansen, “Excision of Mid-Rectal Lesions by the Kraske Sacral Approach,” British Journal of Surgery, Vol. 67, No. 9, 1980, pp. 651-652.
[17] S. Mera-Velasco, A. J. Cabello-Burgos, M. Ruiz-López, et al., “Laparoscopic Resection of an Aggressive Pelvic Angiomyxoma,” Cirugia Espanola (in Spanish), 2009.

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