Poly(N-Vinyl Pyrrolidone-b-Dimethylsiloxane) Electrospun Nanofibers: Preparation, Characterization and Biological Response

DOI: 10.4236/ojbiphy.2013.32018   PDF   HTML   XML   4,338 Downloads   9,866 Views   Citations

Abstract

Here we report electrospinning of Poly(dimethylsiloxane-b-vinyl pyrrolidone) (PDMS-b-PVP) based fibrous scaffold materials. The morphology, thermal properties, surface composition, hydrophilicity and fibers formation with different PDMS and PVP chain lengths were determined by using scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray photoelectron microscopy (XPS) and X-ray diffraction (RXD) water vapor uptake and water contact angle (WCA). The electrospinning parameters were controlled as well as fiber deposition area. The influence of polymer solution concentration on the morphology of electrospun fibers was also investigated. We checked out the applicability of the electrospun fibers for tissue engineering by the investigation of their capability to support fibroblast cell adhesion, cell growth and proliferation.


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I. Keranov, M. Michel, A. Kostadinova, V. Toniazzo, D. Ruch and T. Vladkova, "Poly(N-Vinyl Pyrrolidone-b-Dimethylsiloxane) Electrospun Nanofibers: Preparation, Characterization and Biological Response," Open Journal of Biophysics, Vol. 3 No. 2, 2013, pp. 148-157. doi: 10.4236/ojbiphy.2013.32018.

Conflicts of Interest

The authors declare no conflicts of interest.

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