Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review


Tendinosis is now understood as the result of a failed tendon healing process regardless of where it occurs in the body. Current noninvasive therapeutic alternatives are anti-inflammatory in nature and outcomes are unpredictable at best. The benefit of invasive alternatives resides in the induction of the healing response as demonstrated in pre-clinical and clinical studies in cardiology and orthopaedics. A new technology that employs noninvasivemonopolar capacitive-coupled radiofrequency (mcRF), has demonstrated the ability to raise temperatures in tendons and ligaments upwards of 50°C, the temperature threshold for collagen modulation and recruitment of macrophages, fibroblasts and Heat Shock Protein factors—without damaging the overlying structures—resulting in activation of the Wound Healing Response (WHR).

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T. Whipple and S. Steinmann, "Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review," Open Journal of Orthopedics, Vol. 3 No. 1, 2013, pp. 23-28. doi: 10.4236/ojo.2013.31006.

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The authors declare no conflicts of interest.


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