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Synthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1H-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives

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DOI: 10.4236/ijoc.2012.24051    4,211 Downloads   7,006 Views   Citations


Pyrazoles are important nitrogen containing 5-membered heterocyclic compounds. Numerous pyrazoline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. Several 1,3,5-Triphenyl-1H-pyrazole containing 6-aminopyridazin-3(2H)-one derivatives has been synthesized. These new compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore biological screening of novel compounds has been also done.

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The authors declare no conflicts of interest.

Cite this paper

S. Tupare, S. Dake, S. Nalage, S. Bhosale, R. Ingle and R. Pawar, "Synthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1H-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives," International Journal of Organic Chemistry, Vol. 2 No. 4, 2012, pp. 371-376. doi: 10.4236/ijoc.2012.24051.


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