Synthesis and characterization of hydroxyapatite contain chromium


Hydroxy apatite (HA) is a biocompatible material used as bone-substitute materials in both orthopedics and dentistry due to its excellent osteo-conductive and chemical composition similar to that of the inorganic part of bone in comparison with other implant materials . HA (S1) and Cr loaded hydroxy apatite (S2, S3, S4 and S5) of different chromium concentrations have been prepared. many techniques used to analyze the changes occurred due to the substitution. The XRD (X-ray diffraction) and FTIR (Fourier transform infrared radiation )spectroscopy were used as analytical techniques for the prepared HA and Cr loaded HA. The effect of the heat treatment on structural change of the samples was examined by DTA. It was found that all the samples have the same crystalline structure. The crystallinity of the samples decreased as the chromium ions concentration increase.

Share and Cite:

M. Sallam, S. , M. Tohami, K. , M. Sallam, A. , I. Abo Salem, L. and Adel Mohamed, F. (2012) Synthesis and characterization of hydroxyapatite contain chromium. Journal of Biophysical Chemistry, 3, 278-282. doi: 10.4236/jbpc.2012.34033.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Boanini, E., et al. (2010) Ionic substitution in calcium phosphate synthesized at low temperature. Acat Biomaterial, 6, 1882-1894. Hdoi:10.1016/j.actbio.2009.12.041
[2] Fanovish, M.A., et al. (1998) Improvement of micro structure and micro hardness of hydroxyapatite ceramics by addition of lithium. Material Letters, 33, 269-272. Hdoi:10.1016/S0167-577X(97)00115-8
[3] Atsuo, I., et al. (2002) Zinc releasing calcium phosphate for stimulating bone formation. Material Science and Engineeriing: C, 22, 22-25.
[4] Boukha, Z., Kacimi, M., Figueiredo, J.L., Pereira, M.F.R., Faria, J.L. and Ziyad, M. (2007) Methane dry reforming on Ni loaded hydroxyapatite and fluoroapatite. Applied Catalysis A: General, 317, 299-309. Hdoi:10.1016/j.apcata.2006.10.029
[5] Mabilleau, G., Filmon, R., Petrov, P.K., Baslé, M.F., Sabokbar, A. and Chappard, D. (2010) Cobalt, chromium and nickel affect hydroxyapatite crystal growth in vitro. Act Biomaterialia, 6, 1555-1560. Hdoi:10.1016/j.actbio.2009.10.035
[6] Pang, Y.X. and Bao, X. (2003) Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles. Journal of the European Ceramic Society, 23, 1697-1704. Hdoi:10.1016/S0955-2219(02)00413-2
[7] Elliott, J.C. (1994) Structure and chemistry of the apatitesand other calcium orthophosphates. Elsevier, Amsterdam.
[8] Chantawong, V., Harvey, N.W. and Bashkin, V.N. (2003) Comparison of heavy metaladsorptions by thai kaolin and ballclay. Water, Air, & Soil Pollution, 148, 111-125. Hdoi:10.1023/A:1025401927023
[9] Saxena, S. and D’Souza, S.F. (2006) Heavy metal pollution abatement using rock phosphatemineral. Environment International, 32, 199-202. Hdoi:10.1016/j.envint.2005.08.011
[10] Crosman, A., Gelbard, G., Poncelet, G. and Parvulescu, V.I. (2004) Oxidative dehydrogenation of propane over chromium-loadedcalcium-hydroxyapatite. Applied Catalysis A: General, 23, 264.
[11] Boucetta, C., Kacimi, M., Ensuqueb, A., et al., (2009) Oxidative dehydrogenation of propane over chromium-loaded calcium-hydroxyapatite. Applied Catalysis A: General, 356, 201-210.
[12] Beale, A.M., Grandjean, D., Kornatowski, J., Glatzel, P., De Groot, F.M.F. and Weckhuysen, B.M. (2006) Unusual coordination behavior of Cr3+ in microporous alumino- phosphates. The Journal of Physical Chemistry B, 110, 716-722. Hdoi:10.1021/jp0531006

Copyright © 2021 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.