Lactic Acidosis and Atrial Tachycardia: Unusual Presentations of Disseminated Burkitt-Like Lymphoma

DOI: 10.4236/jct.2012.35075   PDF   HTML     4,222 Downloads   6,445 Views  


Lactic acidosis is a rare complication of malignancies and is seen more frequently in high grade lymphoma and leukemia. Although, its pathogenesis is not well understood, it remains a surrogate of poor prognosis. Herein, we present a case of Burkitt-like lymphoma presenting with metabolic abnormalities including lactic acidosis and hypoglycemia along with atrial tachycardia. We will discuss the different mechanisms involved in these metabolic disturbances and we will provide insight on novel therapeutic strategies based on our understanding of the underlying pathophysiology.

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H. El-Osta, A. Abdulbaki, P. Peddi, A. Takalkar, J. Cotelingam, D. Veillon, A. Vargas, N. Akkus and G. C. Hildebrandt, "Lactic Acidosis and Atrial Tachycardia: Unusual Presentations of Disseminated Burkitt-Like Lymphoma," Journal of Cancer Therapy, Vol. 3 No. 5, 2012, pp. 589-594. doi: 10.4236/jct.2012.35075.

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The authors declare no conflicts of interest.


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