Hysteroscopic septum resection in patients with recurrent abortions and infertility

Davut Güven, Kadir Bakay, Serkan Kuruoğlu, Ayşe Özdemir

Department of Obstetrics and Gynecology, 19 Mayis University School of Medicine, Samsun, Turkey.

DOI: 10.4236/ojog.2012.23054                

Abstract

Objective: The aim of this study was to assess the achievement of pregnancy as well as the reproductive outcome after hysteroscopic septum resection in women with recurrent abortions or infertility. Design: retrospective, clinical trial. Setting: University hospitals. Patient(s): Fourty women with a diagnosis of uterine septum who had a history of pregnancy loss or infertility. They were randomized into two groups. Group I includes 18 infertile women and group II includes 22 recurrent miscarriage women. Intervention(s): Hysteroscopic metroplasty was performed on all patients in both groups. Result(s): 40 patients who were diagnosed with a partial septate uteri had hysteroscopic septum resection and were divided into two groups: Group I (18 patients) presented with infertility and Group II (22 patients) with recurrent abortions. The mean post-operative follow up period was 24 months. Group I, 12 patients (66.6%) and Group II, 17 patients (77.2%) achieved pregnancy, with respective abortion rates of 2 (11.1%) and 4 (18.1%). Conclusion(s): Using hysteroscopy to perform metroplasty on septate uteri makes the procedure safer, easier, and less complicated. This procedure is recommended for all cases diagnosed with an uterine septum.

Keywords

Hysteroscopy; Infertility; Recurrent Abortion; Septum Resection

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Parsanezhad, M.E., Alborzi, S., Zarei, A., Dehbashi, S., Shirazi, L.G., Rajaeefard, A. and Schmidt, E.H. (2006) Hysteroscopic metroplasty of the complete uterine septum, duplicate cervix, and vaginal septum. Fertility & Sterility, 85, 5.
[2]	Fernandez, H., Gervaise, A. and de Tayrac, R. (2000) Operative hysteroscopy for infertility using normal saline solution and a coaxial bipolar electrode: A pilot study. Human Reproduction, 15, 1773-1775. doi:10.1093/humrep/15.6.1425
[3]	Grimbizis, G., Camus, M., Clasen, K., Tournaye, H., De Munck, L. and Devroey, P. (1998) Hysteroscopic septum resection in patients with recurrent abortions or infertility. Human Reproduction, 13, 1188-1193.
[4]	Buttram, C.V. (1983) Müllerian anomalies and their management. Fertility & Sterility, 40, 159-163.
[5]	Moutos, M.D., Damewood, D.M., Schlaff, D.W. and Rock, A.J. (1992) A comparison of the reproductive outcome between women with a unicornuate uterus and women with a didelphic uterus. Fertility & Sterility, 58, 88-93.
[6]	Marcus, S., Al-Shawaf, T. and Brinsden, P. (1996) The obstetric outcome of in vitro fertilization and embryo transfer in women with congenital uterine malformation. American Journal of Obstetrics & Gynecology, 175, 85-89. doi:10.1016/S0002-9378(96)70255-7
[7]	Zikopoulos, K.A., Kolibianakis, E.M., Tournaye, H., de Munck, L., Devroey, P. And Camus M. (2003) Hysteroscopic septum resection using the Versapoint system in subfertile women. Reproductive BioMedicine Online, 7, 365-367.
[8]	Venturoli, S., Colombo, F.M., Vianello, F., Seracchioli, R., Possat, G. and Paradisi R. (2002) A study of hysteroscopic metroplasty in 141 women with a septate uterus. Archives of Gynecology and Obstetrics, 266, 157-159. doi:10.1007/s004040100217