Fine needle aspiration cytology in the diagnosis of multiple myeloma

Luiz Antonio Guimarães Cabral, Andrea Silveira Penteado, Adriana Aigotti Haberbeck Brandão, Janete Dias Almeida

Department of Biosciences and Oral Diagnosis, S?o José dos Campos Dental School, UNESP—Univ Estadual Paulista, S?o José dos Campos, S?o Paulo, Brazil.
Private Practice, Can??o Nova, Cachoeira Paulista, SP, Brazil.

DOI: 10.4236/health.2012.48075                

Abstract

Multiple Myeloma (MM) is a disseminated plasma cell tumor caused by the proliferation of a single plasma cell clone which results from the production of monoclonal immunoglobulin, most commonly class G (IgG). MM is a cancer of the elderly, with a mean age at diagnosis of 68 years. A 79-year-old white patient sought the outpatient clinic of the Discipline of Stomatology, S?o José dos Campos Dental School, UNESP, because of a fracture associated with an osteolytic lesion in the right ascending ramus of the mandible. In view of the clinical-radiographic findings, exploratory fine needle aspiration (FNA) of the lesion was performed and the sanguinolent material obtained was submitted to the preparations of smears for cytology analysis. The diagnosis of MM was based on laboratory and radiographic findings. FNA cytology analysis of the lesion permitted a diagnostic hypothesis of MM.

Keywords

Multiple Myeloma; Diagnostic Imaging; Cytology

Conflicts of Interest

The authors declare no conflicts of interest.

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