Sample Size Determination and Statistical Hypothesis Testing for Core Centration in Press Coated Tablets

Pierre Lafaye de Micheaux, Vincent Lemaire

230 East Grand Avenue South San Francisco CA 94080 USA.
Département de Mathématiques et Statistique Université de Montréal Montréal, Québec, H3T 1J4, Canada.

DOI: 10.4236/ojs.2012.23032                

Abstract

A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This approach is applied to real data.

Keywords

Core Centration; Statistical Hypothesis Testing; Dry-Coated Tablets; Sample Size

Conflicts of Interest

The authors declare no conflicts of interest.

References

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