Pseudo-Meigs syndrome in association with primitive peritoneal tumor

Auriane De Neef, Jean-Christophe Noel, Frédéric Buxant

Department of Gynaecology, Iris Sud Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Department of Pathology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Université Libre de Bruxelles, Brussels, Belgium.

DOI: 10.4236/ojog.2012.22033                

Abstract

We report the case of a 61-year old woman presented with a voluminous centro-pelvic mass (22 × 17 cm), hydrothorax and ascites. Serum CA-125 was high (11,000 UI/ml). An explorative laparotomy located the mass between the rectum and the posterior wall of the uterus. The histological examination showed a primitive peritoneal tumor with serous and endometrioid differentiations. There was a left ovarian metastasis and both peritoneal and pleural liquids revealed no sign of malignancy. After the incomplete surgery, the hydrothorax and ascites decreased considerably. This association of Pseudo-Meigs’ syndrome with primitive peritoneal tumor is uncommon. To our knowledge this is the first case described through a Medline search.

Keywords

Ovarian and Tubal Neoplasms; Peritoneal Neoplasm

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Demons, A. (1887) Epanchements pleurétiques compliquant les kystes de l’ovaire. Bulletin et Memoires de la Societe des Chirurgiens Paris, 13, 771-776.
[2]	Meigs, J.V. and Cass, J. (1937) Fibroma of ovary with ascites and hydrothorax. American Journal of Obstetrics & Gynecology, 33, 249-267.
[3]	Brun, J.L. (2007) Demons syndrome revisited: A review of the literature. Gynecologic Oncology, 105, 796-800. doi:10.1016/j.ygyno.2007.01.050
[4]	Feldman, E.D., Hughes, M.S., Stratton, P., Schrump, D.S.Jr. and Alexander, H.R. (2004) Pseudo-Meigs’ syndrome secondary to isolated colorectal metastasis to ovary: A case report and review of the literature. Gynecologic Oncology, 93, 248-251. doi:10.1016/j.ygyno.2003.12.025
[5]	Fujii, M., Okino, M., Fujioka, K., Yamashita, K. and Hamano, K. (2006) Pseudo-Meigs’ syndrome caused by breast cancer metastasis to both ovaries. Breast Cancer, 13, 344-348. doi:10.2325/jbcs.13.344
[6]	Tessmer, C.S., Barcellos, F.C. and Falchi, L.C. (2005) Pseudo-Meigs’ syndrome associated to renal pelvis tumor. International Brazilian Journal Urology, 31, 256-258. doi:10.1590/S1677-55382005000300010
[7]	Khan, J., McClennan, B.L., Qureshi, S., Martell, M., Lyer, A. and Bokhari, S.J. (2005) Meigs syndrome and gliomatosis peritonei: A case report and review of literature. Gynecologic Oncology, 98, 313-317. doi:10.1016/j.ygyno.2005.03.048
[8]	Migishima, F., Jobo, T., Hata, H., Sato, R., Ikeda, Y., Arai, M. et al. (2000) Uterine leiomyoma causing massive ascites and left pleural effusion with elevated CA 125: A case report. Journal of Obstetrics and Gynecology Research, 26, 283-287. doi:10.1111/j.1447-0756.2000.tb01323.x
[9]	Buckshee, K., Dhond, A.J., Mittal, S. and Bose, S. (1990) Pseudo-Meigs’ syndrome secondary to broad ligament leiomyoma: A case report. Asia-Oceania Journal of Obstetrics and Gynecology, 16, 201-205. doi:10.1111/j.1447-0756.1990.tb00226.x
[10]	Rubinstein, Y., Dashkovsky, I., Cozacov, C. and Hadary, A. (2009) Pseudomeigs’ syndrome secondary to colorectal adenocarcinoma metastasis to the ovaries. Journal of Clinical Oncology, 27, 1334-1336. doi:10.1200/JCO.2008.20.1756