Paediatric amitriptyline overdose

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DOI: 10.4236/ojped.2012.22028    5,612 Downloads   8,777 Views   Citations


We report a near fatal case of paediatric amitriptyline overdose including a series of ECGs demonstrating the effects of sodium bicarbonate therapy on cardio-toxicity. We briefly discuss the role of sodium to counteract the sodium channel blockade of tricyclic antidepressants and discuss the possible utility of lipid emulsion therapy in such cases.

Cite this paper

Doherty, S. , Cave, G. and Harvey, M. (2012) Paediatric amitriptyline overdose. Open Journal of Pediatrics, 2, 170-174. doi: 10.4236/ojped.2012.22028.

Conflicts of Interest

The authors declare no conflicts of interest.


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