Paediatric amitriptyline overdose

Steve Doherty, Grant Cave, Martyn Harvey

Tamworth Rural Referral Hospital, Tamworth, Australia.
Waikato Hospital, Hamilton, New Zealand.

DOI: 10.4236/ojped.2012.22028                

Abstract

We report a near fatal case of paediatric amitriptyline overdose including a series of ECGs demonstrating the effects of sodium bicarbonate therapy on cardio-toxicity. We briefly discuss the role of sodium to counteract the sodium channel blockade of tricyclic antidepressants and discuss the possible utility of lipid emulsion therapy in such cases.

Keywords

Tricyclic Anti-Depressants; Toxicity;Overdose

Conflicts of Interest

The authors declare no conflicts of interest.

References

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