Pattern of occurrence of jaw cysts and cyst-like lesions at the University of Nairobi Dental Hospital: A 10-year histopathologic audit


Background: Jaw cysts and cyst-like lesions cause facial deformity, destruction of dental tissues and affect masticatory and phonation functions. These ad-versely erode patients’ psycho-social status; create low self-esteem and may change one’s facial identity and appearance. Objective: To determine the histo-pathologic characteristics, variants and demographic pattern of jaw cysts and cyst-like lesions at the University of Nairobi Dental Hospital. Material and Me-thod: This was an analytical and verification study that involved microscopic re-examination of all available incisional/excisional biopsy samples from January 2000 to December 2009 for histo-pathological diagnosis at the University of Nairobi Dental Hospital. Results: 187 jaw cysts and cyst-like lesions were diagnosed at the University of Nairobi Dental Hospital over the ten-year period. Keratocystic odontogenic tumours constituted 28%, dentigerous cysts 25%, nasopalatine duct cysts 19%, radicular cysts 15%, while calcifying odontogenic cysts comprised 4% of all the lesions. The rest of the lesions were between 1% and 3% of all the lesion entities. Conclusion: Keratocystic odontogenic tumours and dentigerous cysts were the most common developmental odontogenic cysts diagnosed in the ten-year period.

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Micha, C. , Chindia, M. , Awange, D. , Dimba, E. , Osundwa, T. and Otwoma, J. (2012) Pattern of occurrence of jaw cysts and cyst-like lesions at the University of Nairobi Dental Hospital: A 10-year histopathologic audit. Open Journal of Stomatology, 2, 140-145. doi: 10.4236/ojst.2012.22025.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Yazdani, J. and Kahnamouii, S.S. (2009) Developmental odontogenic cysts of jaws: A clinical study of 245 cases. Journal of Dental Research. Dental Clinics/Dental Prospectus, 3, 64-66.
[2] Jones, A.V., Craig, G.T. and Franklin, C.D. (2006) Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period. Journal of Oral Pathology and Medicine, 35, 500-507. doi:10.1111/j.1600-0714.2006.00455.x
[3] Ochsenius, G., Escobar, E., Godoy, L. and Pe?afiel, C. (2007) Odontogenic cysts: Analysis of 2.944 cases in Chile. Medicina Oral Patologia Oral y Cirugia Bucal, 12, 85-91.
[4] Padayachee, A. and Van Wyk, C.W. (1987) Two cystic lesions with features of both the botryoid odontogenic cyst and the central mucoepidermoid tumour: Sialo-odontogenic cyst. Journal Oral Pathology, 16, 499-504. doi:10.1111/j.1600-0714.1987.tb00680.x
[5] Lacaita, M.G., Saverio, C., Gianfranco, F., et al. (2006) Infected paradental cysts in children: A clinicopathological study of 15 cases. British Journal of Oral and Maxillofacial Surgery, 44, 112-115. doi:10.1016/j.bjoms.2005.03.011
[6] Lucas, C and Blum, T. (1929) Do all cysts of the jaws originate from the dental system. Journal of American Dental Association, 16, 659-661.
[7] Rushton, M. (1946) Solitary bone cysts in the mandible., British Dental Journal, 81, 37-49.
[8] Jaffe, H.L. and Lichtenstein, L. (1942) Solitary unicameral bone cyst with emphasis on the roentgen picture, the pathological appearance and the pathogenesis. Archival Surgery, 44, 1004-1025. doi:10.1001/archsurg.1942.01210240043003
[9] Bemier, J and Bhaskar S. (1958) Aneurysmal bone cyst of the mandible. Oral Surgery, 11, 1018. doi:10.1016/0030-4220(58)90142-7
[10] Grossmann, M.S., Machado, V.C., Guilherme, M.X., et al. (2007) Demographic profile of odontogenic and selected nonodontogenic cysts in a Brazilian population. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 104, 35-41. doi:10.1016/j.tripleo.2007.05.028
[11] Masayuki, T., Jun, C., Satoshi, M., Hiroko, Y., Motowo, N. and Takashi, S. (2008) Perlecan-rich epithelial linings as a background of proliferative potentials of keratocystic odontogenic tumor. Journal of Pathology and Medicine, 37, 287-293. doi:10.1111/j.1600-0714.2007.00620.x
[12] Narasimhan, P.A., Bobby, M.C., Leon B., et al. (2004) Molecular analysis to demonstrate that Odontogenic Keratocysts are neoplastic. Archives of Pathology and Laboratory Medicine, 128, 313-317.
[13] Toida, M. (1998) So-called calcifying odontogenic cyst: Review and discussion on the terminology and classifica- tion. Journal of Oral Pathology and Medicine, 27, 49-52. doi:10.1111/j.1600-0714.1998.tb02092.x
[14] Barnes, L., Eveson, J.W., Reichart, P., et al. (2005) Kera- tocystic odontogenic tumor. World Health Organization classification of tumors; Pathology and genetics of the head and neck tumors. IARC Press, Lyon, 308-309.
[15] Ledesma-Montes, C., Hernández-Guerrero, J.G and Gar- cés-Ortíz, M. (2000) Clinico-pathologic study of odon- togenic cysts in a mexican sample population. Ar-chives of Medical Research, 31, 373-376. doi:10.1016/S0188-4409(00)00069-2
[16] Daley, T.D., Wysocki., G.P. and Pringle, G.A. (1994) Relative incidence of odontogenic tumors and oral jaw cysts in a Canadian population. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology, 77, 276-280.
[17] Weir, L.C., Davemport, W.D. and Skinner, R.L., (1987) A diagnostic and epidemiologic survey of 15,783 oral lesions. Journal of American Dental Association, 115, 439- 442.
[18] Ogunsalu, C., Daisley, H., Kanhai, D., Mankee, M. and Maharaj, A. (2007) Reccurence of odontogenic keratocyst five cases in Jamaica. West Indian Medical Journal, 56, 927-934.
[19] Tortorici, S., Amodio E., Massanti, M., et al. (2008) Prevalence and distribution of odontogenic Cysts in Sicily 1986-2005. Journal of Oral Science, 50, 15-18. doi:10.2334/josnusd.50.15
[20] Koseoglu, B.G., Atalay, B. and Erdem, M.A. (2004) Odontogenic cysts: A clinical study of 90 cases. Journal of Oral Science, 46, 253-257. doi:10.2334/josnusd.46.253
[21] Kramer, I.R.H., Pindborg J.J. and Shear, M. (1992) Histological typing of odontogenic tumours. 2nd Edition, World Health Organization, Geneva.

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