Modification of the Brief Smell Identification Test by Introduction of a Placebo

DOI: 10.4236/nm.2012.32017   PDF   HTML     4,648 Downloads   7,443 Views  

Abstract

Objective: To introduce the concept that there might be “nothing to smell” to the Brief Smell Identification Test (B-SIT), with a view to masking olfactory deficits, particularly from healthy control participants in research studies. Methods: Seventy-one elderly individuals, healthy for their age, were recruited to the study. They were blindfolded and carried out a modified B-SIT where one item had been replaced with a placebo, and one odour alternative answer to three other items was replaced by the alternative “none/other” (actual odour unchanged). Results: There was no overall difference in the median or mean score achieved by the cohort compared to results obtained previously using the conventional B-SIT. The replacement of the item “turpentine” with a placebo resulted in an improved score for the item in a Norwegian setting. The overall scores were not improved. Conclusions: It is possible to introduce the concept that there may be “nothing to smell” to the B-SIT without compromising the test for healthy control individuals. This may be a more appropriate approach to olfactory testing of control individuals or patients with suspected early neurodegenerative diseases.

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G. Kjelvik, O. Bosnes, R. Omli, L. Heidi Skotnes, A. K. Håberg and L. R. White, "Modification of the Brief Smell Identification Test by Introduction of a Placebo," Neuroscience and Medicine, Vol. 3 No. 2, 2012, pp. 125-129. doi: 10.4236/nm.2012.32017.

Conflicts of Interest

The authors declare no conflicts of interest.

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