Correspondence: Newer oral rehydration solution OS-1 for emesis gravidarum


Though nausea and vomiting are quite common in pregnancy, hyperemesis is found in only 1 - 2 patients per 100. Appropriate oral fluid and electrolyte replacement is the initial treatment regimen for patients with mild to moderate emesis to avoid hyperemesis gravidarum defined as dehydration, electrolyte unbalance and ketosis. A newer oral rehydration solution OS-1 therapy may be safe and feasible in the mild to moderate emesis gravidarum population. Physicians are encouraged to use this practice to maintain the amount of water in the body and electrolytes and to improve the patient’s comfort.

Share and Cite:

Imai, A. , Matsunami, K. , Takagi, H. and Ichigo, S. (2012) Correspondence: Newer oral rehydration solution OS-1 for emesis gravidarum. Health, 4, 277-278. doi: 10.4236/health.2012.45045.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Kuscu, N. and Koyuncu, F. (2002) Hyperemesis gravidarum: Current concepts and management. Postgraduated Medical Journal, 78, 76-79. doi:10.1136/pmj.78.916.76
[2] Sheehan, P. (2007) Hyperemesis gravidarum—Assessment and management. Australian Family Physician, 36, 698-701.
[3] Jueckstock, J., Kaestner, R. and Mylonas, I. (2010) Managing hyperemesis gravidarum: A multimodal challenge. BMC Medicine, 8, 46-57. doi:10.1186/1741-7015-8-46
[4] Alves, J., Troster, E. and de Oliveira, C. (2011) Isotonic saline solution as maintenance intravenous fluid therapy to prevent acquired hyponatremia in hospitalized children. Journal of Pediatrics, 87, 476-486.
[5] Itou, K., Fukuyama, T., Sasabuchi, Y., Yasuda, H., Suzuki, N., Hinenoya, H., Kim, C., Sanui, M., Taniguchi, H., Miyao, H., Seo, N., Takeuchi, M., Iwao, Y., Sakamoto, A., Fujita, Y. and Suzuki, T. (2012) Safety and efficacy of oral rehydration therapy until 2 h before surgery: A multicenter randomized controlled trial. Journal of Anesthe-siology, 26, 20-27.
[6] Mizzi, A., Tran, T., Karlnoski, R., Anderson, A., Mangar, D. and Camporesi, E. (2011) Voluven, a new colloid solution. Anesthesiology Clinic, 29, 547-555. doi:10.1016/j.anclin.2011.05.012
[7] Sakurai, Y., Uchida, M., Aiba, J., Mimura, F. and Yamaguchi, M. (2011) Safe practice of oral rehydration therapy by oral rehydration solution and carbohydrate loading— Evaluation by non-invasive gastric echo examination (Japanese Review). Masui, 60, 790-798.

Copyright © 2021 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.