A New and Efficient Method for the Synthesis of Pyrimido[2,1-b]Benzothiazole Derivatives

DOI: 10.4236/ijoc.2012.21006   PDF   HTML     7,158 Downloads   14,502 Views   Citations


The one-pot three-component reaction of 2-aminobenzothiazole, benzaldehyde derivatives and β-ketoester, β-diketone or malonate derivatives in solvent-free conditions provides the corresponding pyrimido [2,1-b] benzothiazole derivatives at 60?C in 60% - 72% yields without using any catalyst in an optimistic time.

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F. Chadegani, F. Darviche and S. Balalaie, "A New and Efficient Method for the Synthesis of Pyrimido[2,1-b]Benzothiazole Derivatives," International Journal of Organic Chemistry, Vol. 2 No. 1, 2012, pp. 31-37. doi: 10.4236/ijoc.2012.21006.

Conflicts of Interest

The authors declare no conflicts of interest.


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