[1]
|
Defronzo, R.A., Ferrannini, E., Groop, L., et al. (2015) Type 2 Diabetes Mellitus. Nature Reviews Disease Primers, 1, Article No. 15019. https://doi.org/10.1038/nrdp.2015.19
|
[2]
|
Saeedi, P., Petersohn, I., Salpea, P., et al. (2019) Global and Regional Diabetes Prevalence Estimates for 2019 and Projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th Edition. Diabetes Research and Clinical Practice, 157, Article ID: 107843. https://doi.org/10.1016/j.diabres.2019.107843
|
[3]
|
IDF (2021) IDF Diabetes Atlas. Tenth Edition.
|
[4]
|
Harding, J.L., Pavkov, M.E., Magliano, D.J., et al. (2019) Global Trends in Diabetes Complications: A Review of Current Evidence. Diabetologia, 62, 3-16.
|
[5]
|
International Diabetes Federation (2020) IDF Diabetes Atlas. 8th Edition.
|
[6]
|
Théry, C., Ostrowski, M. and Segura, E. (2009) Membrane Vesicles as Conveyors of Immune Responses. Nature Reviews Immunology, 9, 581-593. https://doi.org/10.1038/nri2567
|
[7]
|
Mears, R., Craven, R.A., Hanrahan, S., et al. (2004) Proteomic Analysis of Melanoma-Derived Exosomes by Two-Dimensional Polyacrylamide Gel Electrophoresis and Mass Spectrometry. Proteomics, 4, 4019-4031. https://doi.org/10.1002/pmic.200400876
|
[8]
|
Yuan, F.L., Wu, Q., Miao, Z.N., et al. (2018) Osteoclast-Derived Extracellular Vesicles: Novel Regulators of Osteoclastogenesis and Osteoclast-Osteoblasts Communication in Bone Remodeling. Frontiers in Physiology, 9, Article No. 628. https://doi.org/10.3389/fphys.2018.00628
|
[9]
|
Tkach, M. and Théry, C. (2016) Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. Cell, 164, 1226-1232. https://doi.org/10.1016/j.cell.2016.01.043
|
[10]
|
Su, T., Xiao, Y., Xiao, Y., et al. (2019) Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. ACS Nano, 13, 2450-2462. https://doi.org/10.1021/acsnano.8b09375
|
[11]
|
Sun, Y., Shi, H., Yin, S., et al. (2018) Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction. ACS Nano, 12, 7613-7628. https://doi.org/10.1021/acsnano.7b07643
|
[12]
|
Pan, Y., Hui, X., Chong, H.R.L., et al. (2019) Adipocyte-Secreted Exosomal MicroRNA-34a Inhibits M2 Macrophage Polarization to Promote Obesity-Induced Adipose Inflammation. Journal of Clinical Investigation, 129, 834-849. https://doi.org/10.1172/JCI123069
|
[13]
|
Garcia, N.A., Moncayo-Arlandi, J., Sepulveda, P., et al. (2016) Cardiomyocyte Exosomes Regulate Glycolytic Flux in Endothelium by Direct Transfer of GLUT Transporters and Glycolytic Enzymes. Cardiovascular Research, 109, 397-408. https://doi.org/10.1093/cvr/cvv260
|
[14]
|
Besser, R.E.J., Ng, S.M. and Robertson, E.J. (2021) Screening Children for Type 1 Diabetes. BMJ, 375, e067937. https://doi.org/10.1136/bmj-2021-067937
|
[15]
|
Katsarou, A., Gudbjornsdottir, S., Rawshani, A., et al. (2017) Type 1 Diabetes Mellitus. Nature Reviews Disease Primers, 3, Article No. 17016. https://doi.org/10.1038/nrdp.2017.16
|
[16]
|
Schorey, J.S. and Bhatnagar, S. (2008) Exosome Function: From Tumor Immunology to Pathogen Biology. Traffic, 9, 871-881. https://doi.org/10.1111/j.1600-0854.2008.00734.x
|
[17]
|
Pang, H., Luo, S., Xiao, Y., et al. (2020) Emerging Roles of Exosomes in T1DM. Frontiers in Immunology, 11, Article ID: 593348. https://doi.org/10.3389/fimmu.2020.593348
|
[18]
|
Kosaka, N., Iguchi, H., Yoshioka, Y., et al. (2010) Secretory Mechanisms and Intercellular Transfer of microRNAs in Living Cells. Journal of Biological Chemistry, 285, 17442-17452. https://doi.org/10.1074/jbc.M110.107821
|
[19]
|
Montecalvo, A., Larregina, A.T., Shufesky, W.J., et al. (2012) Mechanism of Transfer of Functional microRNAs between Mouse Dendritic Cells via Exosomes. Blood, 119, 756-766. https://doi.org/10.1182/blood-2011-02-338004
|
[20]
|
Valadi, H., Ekstrom, K., Bossios, A., et al. (2007) Exosome-Mediated Transfer of mRNAs and microRNAs Is a Novel Mechanism of Genetic Exchange between Cells. Nature Cell Biology, 9, 654-659. https://doi.org/10.1038/ncb1596
|
[21]
|
Kozomara, A., Birgaoanu, M. and Griffiths-Jones, S. (2019) MiRBase: From microRNA Sequences to Function. Nucleic Acids Research, 47, D155-D162. https://doi.org/10.1093/nar/gky1141
|
[22]
|
Bartel, D.P. (2009) MicroRNAs: Target Recognition and Regulatory Functions. Cell, 136, 215-233. https://doi.org/10.1016/j.cell.2009.01.002
|
[23]
|
Tsui, N.B.Y., Ng, E.K.O. and Lo, Y.M.D. (2002) Stability of Endogenous and Added RNA in Blood Specimens, Serum, and Plasma. Clinical Chemistry, 48, 1647-1653. https://doi.org/10.1093/clinchem/48.10.1647
|
[24]
|
Dumortier, O., Hinault, C. and Van Obberghen, E. (2013) MicroRNAs and Metabolism Crosstalk in Energy Homeostasis. Cell Metabolism, 18, 312-324. https://doi.org/10.1016/j.cmet.2013.06.004
|
[25]
|
Eliasson, L. and Esguerra, J.L.S. (2014) Role of Non-Coding RNAs in Pancreatic Beta-Cell Development and Physiology. Acta Physiologica, 211, 273-284. https://doi.org/10.1111/apha.12285
|
[26]
|
Guay, C. and Regazzi, R. (2016) New Emerging Tasks for microRNAs in the Control of β-Cell Activities. Biochimica et Biophysica Acta—Molecular and Cell Biology of Lipids, 1861, 2121-2129. https://doi.org/10.1016/j.bbalip.2016.05.003
|
[27]
|
Tugay, K., Guay, C., Marques, A.C., et al. (2016) Role of microRNAs in the Age-Associated Decline of Pancreatic Beta Cell Function in Rat Islets. Diabetologia, 59, 161-169. https://doi.org/10.1007/s00125-015-3783-5
|
[28]
|
Grieco, F.A., Sebastiani, G., Juan-Mateu, J., et al. (2017) MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic bh3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells. Diabetes, 66, 100-112. https://doi.org/10.2337/db16-0592
|
[29]
|
Santulli, G. (2018) Exosomal microRNA: The Revolutionary Endogenous Innerspace Nanotechnology. Science Translational Medicine, 10, eaav9141.
|
[30]
|
Garcia-Contreras, M., Shah, S.H., Tamayo, A., et al. (2017) Plasma-Derived Exosome Characterization Reveals a Distinct microRNA Signature in Long Duration Type 1 Diabetes. Scientific Reports, 7, Article No. 5998. https://doi.org/10.1038/s41598-017-05787-y
|
[31]
|
Fan, W., Pang, H., Shi, X., et al. (2022) Plasma-Derived Exosomal mRNA Profiles Associated with Type 1 Diabetes Mellitus. Frontiers in Immunology, 13, Article ID: 995610. https://doi.org/10.3389/fimmu.2022.995610
|
[32]
|
Frorup, C., Mirza, A.H., Yarani, R., et al. (2021) Plasma Exosome-Enriched Extracellular Vesicles from Lactating Mothers with Type 1 Diabetes Contain Aberrant Levels of miRNAs during the Postpartum Period. Frontiers in Immunology, 12, Article ID: 744509. https://doi.org/10.3389/fimmu.2021.744509
|
[33]
|
Pablo, A., Evelyn, B., Claudia, F., et al. (2020) GLP-1RA and SGLT2i: Cardiovascular Impact on Diabetic Patients. Current Hypertension Reviews, 17, 149-158. https://doi.org/10.2174/1573402116999201124123549
|
[34]
|
Ling, C. and Ronn, T. (2019) Epigenetics in Human Obesity and Type 2 Diabetes. Cell Metabolism, 29, 1028-1044. https://doi.org/10.1016/j.cmet.2019.03.009
|
[35]
|
Mastrototaro, L. and Roden, M. (2021) Insulin Resistance and Insulin Sensitizing Agents. Metabolism, 125, Article ID: 154892. https://doi.org/10.1016/j.metabol.2021.154892
|
[36]
|
Galic, S., Oakhill, J.S. and Steinberg, G.R. (2010) Molecular and Cellular Endocrinology Adipose Tissue as an Endocrine Organ. Molecular and Cellular Endocrinology, 316, 129-139. https://doi.org/10.1016/j.mce.2009.08.018
|
[37]
|
Thomou, T., Mori, M.A., Dreyfuss, J.M., et al. (2017) Adipose-Derived Circulating miRNAs Regulate Gene Expression in Other Tissues. Nature, 542, 450-455. https://doi.org/10.1038/nature21365
|
[38]
|
Ying, W., Riopel, M., Bandyopadhyay, G., et al. (2017) Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate in Vivo and in Vitro Insulin Sensitivity. Cell, 171, 372-384.e12. https://doi.org/10.1016/j.cell.2017.08.035
|
[39]
|
Crewe, C., Joffin, N., Rutkowski, J.M., et al. (2018) An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State. Cell, 175, 695-708.e13. https://doi.org/10.1016/j.cell.2018.09.005
|
[40]
|
Bassil, F., Canron, M.H., Vital, A., et al. (2017) Insulin Resistance and Exendin-4 Treatment for Multiple System Atrophy. Brain, 140, 1420-1436. https://doi.org/10.1093/brain/awx044
|
[41]
|
Watt, M.J., Miotto, P.M., De Nardo, W., et al. (2019) The Liver as an Endocrine Organ—Linking NAFLD and Insulin Resistance. Endocrine Reviews, 40, 1367-1393. https://doi.org/10.1210/er.2019-00034
|
[42]
|
Yu, Y., Du, H., Wei, S., et al. (2018) Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle through Repression of PPARγ. Theranostics, 8, 2171-2188. https://doi.org/10.7150/thno.22565
|
[43]
|
Chen, T., Zhang, Y., Liu, Y., et al. (2019) miR-27a Promotes Insulin Resistance and Mediates Glucose Metabolism by Targeting PPAR-γ-Mediated PI3K/AKT Signaling. Aging, 11, 7510-7524. https://doi.org/10.18632/aging.102263
|
[44]
|
Kumar, A., Ren, Y., Sundaram, K., et al. (2021) miR-375 Prevents High-Fat Diet-Induced Insulin Resistance and Obesity by Targeting the Aryl Hydrocarbon Receptor and Bacterial Tryptophanase (tnaA) Gene. Theranostics, 11, 4061-4077. https://doi.org/10.7150/thno.52558
|
[45]
|
Chen, S.H., Liu, X.N. and Peng, Y. (2019) MicroRNA-351 Eases Insulin Resistance and Liver Gluconeogenesis via the PI3K/AKT Pathway by Inhibiting FLOT2 in Mice of Gestational Diabetes Mellitus. Journal of Cellular and Molecular Medicine, 23, 5895-5906. https://doi.org/10.1111/jcmm.14079
|
[46]
|
Wang, Y., Li, M., Chen, L., et al. (2021) Natural Killer Cell-Derived Exosomal miR-1249-3p Attenuates Insulin Resistance and Inflammation in Mouse Models of Type 2 Diabetes. Signal Transduction and Targeted Therapy, 6, Article No. 409. https://doi.org/10.1038/s41392-021-00805-y
|
[47]
|
Xu, H., Du, X., Xu, J., et al. (2020) Pancreatic β Cell microRNA-26a Alleviates Type 2 Diabetes by Improving Peripheral Insulin Sensitivity and Preserving β Cell Function. PLOS Biology, 18, e3000603. https://doi.org/10.1371/journal.pbio.3000603
|
[48]
|
Dowarah, J. and Singh, V.P. (2020) Anti-Diabetic Drugs Recent Approaches and Advancements. Bioorganic & Medicinal Chemistry, 28, Article ID: 115263.
|
[49]
|
Laakso, M. (2019) Biomarkers for Type 2 Diabetes. Molecular Metabolism, 27S, S139-S146. https://doi.org/10.1016/j.molmet.2019.06.016
|
[50]
|
Fan, B. (2019) Novel Biomarkers for Cardiovascular and Renal Complications in Chinese with Type 2 Diabetes. Dissertations, The Chinese University of Hong Kong, Hong Kong.
|
[51]
|
Arneth, B., Arneth, R. and Shams, M. (2019) Metabolomics of Type 1 and Type 2 Diabetes. International Journal of Molecular Sciences, 20, Article No. 2467. https://doi.org/10.3390/ijms20102467
|
[52]
|
López-Pastor, A.R., Infante-Menéndez, J., Escribano, ó., et al. (2020) miRNA Dysregulation in the Development of Non-Alcoholic Fatty Liver Disease and the Related Disorders Type 2 Diabetes Mellitus and Cardiovascular Disease. Frontiers in Medicine (Lausanne), 7, Article ID: 527059. https://doi.org/10.3389/fmed.2020.527059
|
[53]
|
Cole, J.B. and Florez, J.C. (2020) Genetics of Diabetes Mellitus and Diabetes Complications. Nature Reviews Nephrology, 16, 377-390. https://doi.org/10.1038/s41581-020-0278-5
|
[54]
|
International Diabetes Federation [IDF] (2017) IDF Diabetes Atlas. 8th Edition.
|
[55]
|
Petrie, J.R., Guzik, T.J. and Touyz, R.M. (2018) Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms. Canadian Journal of Cardiology, 34, 575-584. https://doi.org/10.1016/j.cjca.2017.12.005
|
[56]
|
International Diabetic Federation (2016) International Diabetic Federation Annual Report 2016. Nature Genetics, 38, 320-323. http://www.ncbi.nlm.nih.gov/pubmed/16415884
|
[57]
|
Mcclelland, A.D. and Kantharidis, P. (2014) MicroRNA in the Development of Diabetic Complications. Clinical Science, 126, 95-110.
|
[58]
|
Chi, T., Lin, J., Wang, M., et al. (2021) Non-Coding RNA as Biomarkers for Type 2 Diabetes Development and Clinical Management. Frontiers in Endocrinology, 12, Article ID: 630032. https://doi.org/10.3389/fendo.2021.630032
|
[59]
|
Li, H., Fan, J., Zhao, Y., et al. (2019) Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart. Circulation Research, 125, 1106-1120. https://doi.org/10.1161/CIRCRESAHA.119.314898
|
[60]
|
Barutta, F., Tricarico, M., Corbelli, A., et al. (2013) Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy. PLOS ONE, 8, e73798. https://doi.org/10.1371/journal.pone.0073798
|
[61]
|
Li, J., Jiang, X., Duan, L., et al. (2019) Long Non-Coding RNA MEG3 Impacts Diabetic Nephropathy Progression through Sponging miR-145. American Journal of Translational Research, 11, 6691-6698. http://www.ncbi.nlm.nih.gov/pubmed/31737219
|
[62]
|
Wei, B., Liu, Y. and Guan, H. (2020) MicroRNA-145-5p Attenuates High Glucose-Induced Apoptosis by Targeting the Notch Signaling Pathway in Podocytes. Experimental and Therapeutic Medicine, 19, 1915-1924. https://doi.org/10.3892/etm.2020.8427
|