Author(s)

Lusine Gasparyan^1,2, Ilya Mazo¹, Vahan Simonyan³, Ferdinand Gasparyan^1,2

¹Argentys Informatics, LLC, Gaithersburg MD, USA.
²Yerevan State University, Yerevan, Armenia.
³The Department of Biochemistry & Molecular Medicine, The School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.

In this review, we collected and classified the stages of development of DNA sequencing methods and described its peculiarities. We pay attention mostly on solid-stead nanopore sequencing methods. Detailed discussion of the peculiarity and feasibility of the electrical methods of DNA sequencing is discussed. The detail analyses of the literature data, some critical considerations and the potential ways of optimization of DNA nanopore sequencing were presented.

DNA Sequencing, ISFET Sensor, EIS Sensor, Solid-Stead Nanopore

Gasparyan, L. , Mazo, I. , Simonyan, V. and Gasparyan, F. (2019) DNA Sequencing: Current State and Prospects of Development. Open Journal of Biophysics, 9, 169-197. doi: 10.4236/ojbiphy.2019.93013.