Author(s)

Bangaly Traore^1*, Abdoulaye Toure², Telly Sy³, Mamadou Moustapha Dieng⁴, Mamoudou Condé¹, Ahmadou Deme⁴, Namory Keita³

¹Surgical Oncology Unit of Donka, University Hospital of Conakry, Conakry, Guinea.
²Department of Pharmacy, University of Conakry, Conakry, Guinea.
³Department of Gyneacology and Obstetric, Teaching Hospital of Conakry, Conakry, Guinea.
⁴Cancer Institute of Dakar, Dakar, Senegal.

Background: We aim to review different factors associated with the relapse and the mortality in breast cancer patients in restricted-resource settings over a five-year period. Method: A retrospective cohort study including 133 women underwent breast cancer surgery was performed at the Surgical Oncology Unit of the Conakry University Hospital in Guinea. Socio-demographical characteristics, clinical information, treatment and data on relapse and survival were retrieved from medical files. Predictor factors of relapse were analyzed by using univariate and multivariate logistic regression. Factors associated with mortality were analyzed by Kaplan Meier survival and Cox models. Results: Breast cancer surgery was conservative in 13 cases (9.8%) and radical in 120 cases (90.2%). Five-year relapse was 33.8% ± 8.0% and the predictor factors of this relapse were age and stage III (p = 0.005). The overall 5-year mortality was 42.1% and the risk factors independently associated with death were body mass index (p = 0.01), origin of patients (p = 0.02), radiotherapy (p = 0.01) and cancer relapse (p = 0.001). Conclusion: The proportions of relapse and death were higher in breast cancer patients. The age and the stage of cancer at the time of surgery were the predictor factors of relapse. Body mass index, origin of patients, radiotherapy and cancer relapse were associated with death.

Breast Cancer, Breast Surgery, Prognosis, Developing Countries

Traore, B. , Toure, A. , Sy, T. , Dieng, M. , Condé, M. , Deme, A. and Keita, N. (2015) Prognosis of Breast Cancer Patients Underwent Surgery in a Developing Country. Journal of Cancer Therapy, 6, 803-810. doi: 10.4236/jct.2015.69088.