Author(s)

Maduike C. O. Ezeibe, Antony N. Egbuji, Obianuju N. Okoroafor, James I. Eze, Omadi Ijabo, Augustine A. Ngene, Ikechukwu C. Eze, Joseph A. C. Ugonabo, Mary E. Sanda, Ijeoma J. Mbuko

Department of Microbiology, University of Nigeria, Nsukka, Nigeria.
Department of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.
Viral Research Laboratory, National Veterinary Research Institute, Vom, Nigeria.

Effects a synthetic Aluminium-Magnesium Silicate [AMS] has on Avian Influenza Virus (AIV) were tested. Equal amounts of AIV samples and of the AMS were mixed, kept one hour at room temperature before centrifuging. The supernatants were remeasured and tested for, viral titre, Mean Death Time (MDT) and Mortality Rate of chicken Embryos (EMR). Volumes of the viral samples reduced at rate of 23.4% ± 5.48%. Viral titres reduced significantly (P < 0.01) from HA, 73 ± 32.72 to 1.4 ± 0.43. Also, EMR of infected chicken embryos reduced from 100% to 65%, while MDT of those that died,increased significantly (P < 0.01) from 76 ± 4.38 to 136 ±18.93 hours. When incubation with AMS was repeated on portions of an AIV sample, MDT increased from 64 to 104 hours with the portion incubated once. AIV portions on which incubation with AMS was repeated could not kill chicken embryos.

Antiviral; Synthetic Aluminium-Magnesium Silicate; Avian Influenza Virus

Ezeibe, M. , Egbuji, A. , Okoroafor, O. , Eze, J. , Ijabo, O. , Ngene, A. , Eze, I. , Ugonabo, J. , Sanda, M. and Mbuko, I. (2012) Antiviral effects of a synthetic Aluminium-Magnesium Silicate, on Avian Influenza Virus. Health, 4, 429-432. doi: 10.4236/health.2012.47067.