Author(s)

Yixue Liu^1,2,3, Xiaoping Tan^1,2,3*

¹Department of Gastroenterology, First Hospital of Yangtze University, Jingzhou, China.
²Digestive Disease Research Institution of Yangtze University, Jingzhou, China.
³Clinical Medical College, Yangtze University, Jingzhou, China.

Inflammatory bowel disease (IBD) is a group of chronic, nonspecific intestinal inflammatory disorders characterized by localized and systemic inflammation. The use of biologic agents in the treatment of IBD patients is widespread, and the occurrence of primary non-responsiveness during treatment is also significant. This review briefly summarizes the possible reasons for primary non-responsiveness in IBD patients, as well as predictive markers and current strategies to address it, providing a theoretical reference for early identification and management of IBD patients who do not respond to treatment.

Inflammatory Bowel Disease, Primary Non-Responsiveness , Anti-Tumor Necrosis Factor

Liu, Y. and Tan, X. (2024) Progress in the Study of Inflammatory Bowel Disease Patients with Primary Non-Responsiveness. Journal of Biosciences and Medicines, 12, 72-85. doi: 10.4236/jbm.2024.121007.