Author(s)

Ibtisam Alqahtani^1*, Sharefa Eisa Ali Alhazmi²

¹Umm Al-Qura University Mathematics department, Makkah, Saudi Arabia.
²Department of Mathematics, University College in Qunfudah, Umm Al-Qura University, Makkah, Saudi Arabia.

A brain tumor occurs when abnormal cells grow, sometimes very rapidly, into an abnormal mass of tissue. The tumor can infect normal tissue, so there is an interaction between healthy and infected cell. The aim of this paper is to propose some efficient and accurate numerical methods for the computational solution of one-dimensional continuous basic models for the growth and control of brain tumors. After computing the analytical solution, we construct approximations of the solution to the problem using a standard second order finite difference method for space discretization and the Crank-Nicolson method for time discretization. Then, we investigate the convergence behavior of Conjugate gradient and generalized minimum residual as Krylov subspace methods to solve the tridiagonal toeplitz matrix system derived.

PDEs, Krylov Subspace Methods, Finite Difference, Toeplitz Matrix, Two-Cell Model, Tumor Interaction Modeling

Alqahtani, I. and Alhazmi, S. (2023) Modeling One Dimensional Two-Cell Model with Tumor Interaction Using Krylov Subspace Methods. Applied Mathematics, 14, 21-34. doi: 10.4236/am.2023.141002.