Author(s)

Yoro Tine^1,2*, Alioune Diallo^1,2, Idrissa Ndoye¹, Cheikhouna Gaye¹, Benjamin Ndiaye¹, Abdoulaye Diop³, Jean Costa², Cheikh Saad Bouh Boye³, Alassane Wélé¹, Julien Paolini²

¹Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Senegal.
²Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, Corte, France.
³Laboratoire de Bactériologie-virologie, Hôpital Aristide Le Dantec, Dakar, Senegal.

1,8-cineole, also known as eucalyptol, is the main constituent and the most important of the leaf oils of many species of the genus Eucalyptus. In present study, the essential oils isolated by hydrodistillation from the leaves of Eucalyptus camaldulensis from six different locations were analyzed by GC-FID and GC-MS. Essential oil yields ranged from 0.33% to 4.35%. In total, 34 constituents were identified, accounting for 94.0% to 99.8% of the total compositions. 1,8-cineole (46.4% - 84.4%) was the main constituent of all the essential oil samples, except for one sample collected in the Fatick region, which had p-cymene (46.4%) and 1,8-cineole (26.0%) as major compounds. The essential oil showed excellent activity against S. aureus, E. coli and E. faecalis (IZ = 25.3 ± 1.2 mm; 18.7 ± 0.6 mm; 17.8 ± 0.3 mm, respectively) and moderate activity against P. aeruginosa (IZ = 10.8 ± 0.8 mm). They may have potential applications in food and pharmaceutical products.

Eucalyptus camaldulensis, Essential Oils, Antibacterial Activity, 1, 8-Cineole and GC-SM

Tine, Y. , Diallo, A. , Ndoye, I. , Gaye, C. , Ndiaye, B. , Diop, A. , Costa, J. , Bouh Boye, C. , Wélé, A. and Paolini, J. (2022) Chemical Variability and Antibacterial Activity of Eucalyptus camaldulensis Essential Oils from Senegal. International Journal of Organic Chemistry, 12, 173-180. doi: 10.4236/ijoc.2022.124014.