Author(s)

Lamzira Parulava, Levani Eliashvili^*, Vakhtang Betlemidze, Natia Mzareulishvili

National High Technology Center of Georgia, Vake-Saburtalo, Tbilisi, Georgia.

Nitrogen-15 isotope-modified compounds are widely used in medicine, pharmacology, agriculture and various fields of science and their nomenclature is gradually increasing. Their widespread use depends on the availability of inexpensive and simple isotope analysis methods. The present article is an attempt to determine the nitrogen-15 isotope content directly in organic compounds without their conversion. The general principle of possibility of determination of the isotopes of nitrogen directly in organic compounds is proposed. Based on the study of mass-spectra of Carbamide Carbonyldiamide, isocyanic acid and nitrobenzene the mass peaks are selected, by which it is possible to determine the atomic fraction of the isotopes of nitrogen. The respective formulas are proposed.

Atomic Fraction, Isotope, Nitrogen, Molecular Ions, Mass Spectrometer, Mass Spectrum, Monoisotopic Forms, Carbamide Carbonyldiamide (Urea), Isocyanic Acid, Nitrobenzene, Isotope Analysis, Isotope-Modified Compound, Nitrogen Center, Monoisotopic Form, Two Different Nitrogen Centers

Parulava, L. , Eliashvili, L. , Betlemidze, V. and Mzareulishvili, N. (2022) Mass-Spectrometric Method of Measurement of Isotopic Content of Nitrogen in Organic Compounds. American Journal of Analytical Chemistry, 13, 186-194. doi: 10.4236/ajac.2022.135013.