Author(s)

Tudor Florin Ursuleanu^1,2,3, Andreea Roxana Luca^1,4, Liliana Gheorghe^1,5, Roxana Grigorovici¹, Stefan Iancu¹, Maria Hlusneac¹, Cristina Preda^1,6, Alexandru Grigorovici^1,2

¹Faculty of General Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania.
²“Sf. Spiridon” Hospital, Department of Surgery VI, Iasi, Romania.
³Regional Institute of Oncology, Department of Surgery I, Iasi, Romania.
⁴Integrated Ambulatory of Hospital “Sf. Spiridon”, Department of Obstetrics and Gynecology, Iasi, Romania.
⁵“Sf. Spiridon” Hospital, Department of Radiology, Iasi, Romania.
⁶“Sf. Spiridon” Hospital, Department of Endocrinology, Iasi, Romania.

Rationale and Objectives: Accurately establishing the diagnosis and staging of cervical and thyroid cancers is essential in medical practice in determining tumor extension and dissemination and involves the most accurate and effective therapeutic approach. For accurate diagnosis and staging of cervical and thyroid cancers, we aim to create a diagnostic method, optimized by the algorithms of artificial intelligence and validated by achieving accurate and favorable results by conducting a clinical trial, during which we will use the diagnostic method optimized by artificial intelligence (AI) algorithms, to avoid errors, to increase the understanding on interpretation computer tomography (CT) scan, magnetic resonance imaging (MRI) of the doctor and improve therapeutic planning. Materials and Methods: The optimization of the computer assisted diagnosis (CAD) method will consist in the development and formation of artificial intelligence models, using algorithms and tools used in segmental volumetric constructions to generate 3D images from MRI/CT. We propose a comparative study of current developments in “DICOM” image processing by volume rendering technique, the use of the transfer function for opacity and color, shades of gray from “DICOM” images projected in a three-dimensional space. We also use artificial intelligence (AI), through the technique of Generative Adversarial Networks (GAN), which has proven to be effective in representing complex data distributions, as we do in this study. Validation of the diagnostic method, optimized by algorithm of artificial intelligence will consist of achieving accurate results on diagnosis and staging of cervical and thyroid cancers by conducting a randomized, controlled clinical trial, for a period of 17 months. Results: We will validate the CAD method through a clinical study and, secondly, we use various network topologies specified above, which have produced promising results in the tasks of image model recognition and by using this mixture. By using this method in medical practice, we aim to avoid errors, provide precision in diagnosing, staging and establishing the therapeutic plan in cancers of the cervix and thyroid using AI. Conclusion: The use of the CAD method can increase the quality of life by avoiding intra and postoperative complications in surgery, intraoperative orientation and the precise determination of radiation doses and irradiation zone in radiotherapy.

Artificial Intelligence, Cervical Cancer, Thyroid Cancer, MRI Images, CT Images

Ursuleanu, T. , Luca, A. , Gheorghe, L. , Grigorovici, R. , Iancu, S. , Hlusneac, M. , Preda, C. and Grigorovici, A. (2021) The Use of Artificial Intelligence on Segmental Volumes, Constructed from MRI and CT Images, in the Diagnosis and Staging of Cervical Cancers and Thyroid Cancers: A Study Protocol for a Randomized Controlled Trial. Journal of Biomedical Science and Engineering, 14, 300-304. doi: 10.4236/jbise.2021.146025.