The study investigated the knowledge and attitude towards cervical cancer in Imo State, Nigeria. A sample of 230 female undergraduate students selected from Imo State University participated in the study. Data were collected using structured questionnaire and were analyzed using percentage, mean and Chi-Square. The result showed that the majority (81.7%) of the respondents were in their sexually active ages, the majority (70.0%) of the respondents had a low knowledge of cervical cancer and about 53% did not know about its causes. On the attitude towards screening, 82.6% of the respondents had never done pap smear test and 80% were afraid of going for it. The result further showed a generally negative belief about cervical cancer infection. The hypothesis tested showed a significant relationship between level of knowledge and attitude towards cervical cancer screening at p = 0.000. Therefore, increased sensitization targeting women in sexually active ages as a way of improving their knowledge on cervical cancer was recommended.