Evaluation of Adverse Events Following Immunization against Rotavirus Regardless of Recommended Age Restriction ()
ABSTRACT
Introduction: Mild
and moderate Adverse Events Following Immunization (AEFI) against Rotavirus has
not received much attention when the vaccine is administered regardless of
recommended age restriction. Objectives: To describe the behavior of
mild and moderate AEFI in immunized subjects against Rotavirus, in who age
restriction period had not been considered. Methods: A case-control
study in which we included immunized patients with monovalent oral vaccine
against rotavirus and divided them into two groups: 1) Infants who received RV1
vaccine without considering the recommended period, and 2) Infants who were
vaccinated with the recommended schedule. Results: From the total doses,
143/1894 (7.5%) were administered outside the restriction period. The most
frequent AEFIs with the first dose were purpura, polypnea, and rhinorrhea; For the second dose: purpura,
bloody stools, irritability and rhinorrhea. Conclusions: This study
shows the benefits from vaccination regardless of age restriction are more
beneficial compared to the possible risks of AEFI.
Share and Cite:
Reyna-Figueroa, J. , Bercholc-Urinowsky, I. , Cardoso-Yah, G. , Vazquez-Alvarado, R. , Ramos-López, D. , Campos-Romero, F. , Handelsman, C. and Limón-Rojas, A. (2017) Evaluation of Adverse Events Following Immunization against Rotavirus Regardless of Recommended Age Restriction.
Journal of Biosciences and Medicines,
5, 78-82. doi:
10.4236/jbm.2017.58006.
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