Renal Manifestations among Adult Sickle Cell Disease Patients: A Single Center Study in Khartoum, Sudan - Open Journal of Nephrology

OJNeph > Vol.6 No.4, December 2016

Open Journal of Nephrology

Volume 6, Issue 4 (December 2016)

ISSN Print: 2164-2842 ISSN Online: 2164-2869

Google-based Impact Factor: 0.48 Citations

Renal Manifestations among Adult Sickle Cell Disease Patients: A Single Center Study in Khartoum, Sudan ()

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DOI: 10.4236/ojneph.2016.64020 1,553 Downloads 2,965 Views Citations

Author(s)

Amin S. Banaga^1*, Hala I. Elhardlu², Khalifa Elmusharaf³

Affiliation(s)

¹Department of Medicine & Nephrology, University of Medical Sciences and Technology, Academy Charity Teaching Hospital, Khartoum, Sudan.
²Clinical Research Assistants, Department of Nephrology, Academy Charity Teaching Hospital, Khartoum, Sudan.
³Graduate Entry Medical School, University of Limerick, Ireland.

ABSTRACT

Sickle Cell Disease (SCD) in adults is one of the causes of renal abnormalities and Chronic Kidney Disease (CKD). In this retrospective study, we explore the renal manifestations among adult SCD patients. The subjects of the study are all adult patients diagnosed with sickle cell anaemia and admitted as to the Academy Charity Teaching Hospital, Khartoum/Sudan during the period (01/01/2015-31/12/2015). All adult SCD patients’ medical files have been reviewed focusing on personal and clinical data in addition to presence or absence of renal manifestations, a total of 51 adult patients with SCD have been admitted to Academy Charity Teaching Hospital, Khartoum/ Sudan. 11 patients have renal manifestations (21.5%). The mean age ± SD of SCD patients with renal manifestations was 20.2 ± 1.9 years, 63.6% were males, the mean Hb level was 6.9 ± 0.99 gm/dl, proteinuria was present among 81.8% of patients, followed by haematuria (36.4%) and End Stage Renal Failure (ESRF) (18.2%). Further prospective studies are needed to explore the renal abnormalities among adult SCD patients.

KEYWORDS

Sickle Cell Disease, Renal Manifestations, Sudan

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Banaga, A. , Elhardlu, H. and Elmusharaf, K. (2016) Renal Manifestations among Adult Sickle Cell Disease Patients: A Single Center Study in Khartoum, Sudan. Open Journal of Nephrology, 6, 157-160. doi: 10.4236/ojneph.2016.64020.

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