Infectious diseases detection by microarray: An overview of clinical relevant infections - Journal of Biomedical Science and Engineering

JBiSE > Vol.6 No.10, October 2013

Journal of Biomedical Science and Engineering

Volume 6, Issue 10 (October 2013)

ISSN Print: 1937-6871 ISSN Online: 1937-688X

Google-based Impact Factor: 0.66 Citations h5-index & Ranking

Infectious diseases detection by microarray: An overview of clinical relevant infections ()

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Download as PDF (Size: 81KB) PP. 1006-1013

DOI: 10.4236/jbise.2013.610125 8,506 Downloads 12,717 Views Citations

Author(s)

Sara Elisa Herrera-Rodriguez, Darwin Elizondo-Quiroga, Ikuri Alvarez-Maya

Affiliation(s)

Department of Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design in State of Jalisco (CIATEJ), Guadalajara, México.

ABSTRACT

Microarray technology is a powerful tool to investigate whole genome expression profiles to study the crosstalk between pathogens and associated hosts that cause illness. Microarrays have been used in several comparative genome hybridization studies of pathogens. In addition to detection and identification of pathogens, microarrays are ideal for characterizing genetic differences between bacteria isolates of the same species to the strain level. Furthermore, the use of microarrays has been gaining importance in the detection of viral agents. Here we explore the use of microarrays for simultaneous detection of viruses and modifications made over these techniques. Microarray technology has also been incorporated to compensate for time-consuming sequencing. The procedure of fungi identification based on sequences and studies reported the use of microarrays to identify pathogenic yeasts and molds by targeting the internal transcribed spacer regions in fungal rRNA genes. The remarkable advancement in genomics over the last decade has made it possible for microarray technology to evolve towards being the best option for clinical diagnostics because they have several advantages.

KEYWORDS

DNA Microarray; Diagnosis; Bacteria; Virus; Fungi

Share and Cite:

Herrera-Rodriguez, S. , Elizondo-Quiroga, D. and Alvarez-Maya, I. (2013) Infectious diseases detection by microarray: An overview of clinical relevant infections. Journal of Biomedical Science and Engineering, 6, 1006-1013. doi: 10.4236/jbise.2013.610125.

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