Mesenchymal stem cells for the treatment of tendon disorders - Journal of Biomedical Science and Engineering

JBiSE > Vol.6 No.8, August 2013

Journal of Biomedical Science and Engineering

Volume 6, Issue 8 (August 2013)

ISSN Print: 1937-6871 ISSN Online: 1937-688X

Google-based Impact Factor: 0.66 Citations h5-index & Ranking

Mesenchymal stem cells for the treatment of tendon disorders ()

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DOI: 10.4236/jbise.2013.68A1002 4,464 Downloads 6,605 Views Citations

Author(s)

Lucia Machová Urdzíková, Petr Lesný, Eva Syková, Pavla Jendelová

Affiliation(s)

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic.

ABSTRACT

Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are the most suitable candidates for such therapies due to their capacity to differentiate into cells of mesodermal origin, their paracrine properties and their potential use in autologous transplantation. This review summarizes experimental as well as clinical data focusing on the use of mesenchymal stem cells to treat tendinophaties.

KEYWORDS

Tendinophaty; Tendinosis; Tendonitis; Models of Tendon Injuries; Mesenchymal Stem Cells; Rotator Cuff; Achilles Tendon; Tendon Rupture

Share and Cite:

Urdzíková, L. , Lesný, P. , Syková, E. and Jendelová, P. (2013) Mesenchymal stem cells for the treatment of tendon disorders. Journal of Biomedical Science and Engineering, 6, 14-23. doi: 10.4236/jbise.2013.68A1002.

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