This paper develops a prototype to demonstrate a full-duplex wireless visible light communication (VLC) system based on Universal Serial Bus (USB) port. Combing with a USB 2.0 port on one board, it can achieve up to 2 Mbps bit rates error free, which is mainly limited to the USB bridge circuit, between two computers for data transmission, such as text, audio and video. Hyper Terminal and self-written software are used to allow setting the transmission data rate, control bits, check bits and achieve real-time transmission between any two mobile devices with a USB port. The work is based on the research of VLC local access network. This paper also shows the experimental results and the relationship between system transmission eye diagram and bit rate.