Journal of Biomedical Science and Engineering

Volume 6, Issue 2 (February 2013)

ISSN Print: 1937-6871   ISSN Online: 1937-688X

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Ezetimibe Completely Replaced LDL-Apheresis for the Treatment of Familial Hypercholesterolemia and Coronary Artery Disease after CABG—A Case Report

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DOI: 10.4236/jbise.2013.62A028    4,760 Downloads   8,024 Views  
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ABSTRACT

Intensive treatment of hyperlipidemia is an important factor in the prevention of cardiovascular disease. Among several therapies, statins are well recognized as playing a central role, although low density lipoprotein bound cholesterol-apheresis can be used to treat very severe cases of familial hypercholesterolemia. However, statins are not always effective on their own and, recently, ezetimibe has emerged as a unique anti- hypercholesterolemic drug that acts as a cholesterol transporter inhibitor; its role is only partially understood. I experienced rare case that appeared to benefit from ezetimibe therapy, and report them as they help increase our knowledge of this novel drug.

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Yokoyama, I. (2013) Ezetimibe Completely Replaced LDL-Apheresis for the Treatment of Familial Hypercholesterolemia and Coronary Artery Disease after CABG—A Case Report. Journal of Biomedical Science and Engineering, 6, 232-235. doi: 10.4236/jbise.2013.62A028.

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