The Pathophysiology of Cellulite: Can the Puzzle Eventually Be Solved? - Journal of Cosmetics, Dermatological Sciences and Applications

JCDSA > Vol.2 No.1, March 2012

Journal of Cosmetics, Dermatological Sciences and Applications

Volume 2, Issue 1 (March 2012)

ISSN Print: 2161-4105 ISSN Online: 2161-4512

Google-based Impact Factor: 0.33 Citations

The Pathophysiology of Cellulite: Can the Puzzle Eventually Be Solved? ()

HTML

Download as PDF (Size: 260KB) PP. 1-7

DOI: 10.4236/jcdsa.2012.21001 8,383 Downloads 15,315 Views Citations

Author(s)

Ilja Kruglikov

Affiliation(s)

Wellcomet GmbH, Karlsruhe, Germany..

ABSTRACT

The pathophysiology of cellulite is still largely unknown. Here, we propose a new pathophysiology that connects the development of cellulite with several newly-discovered hallmarks of white adipose tissue. According to this theory, cellulite appears in hypertrophic fat tissue that is associated with overproduction of low molecular weight hyaluronan (HA). This can induce different types of fibrosis, producing inhomogeneous spatial tension in the tissue. This pathophysiology serves to explain the most well known peculiarities of cellulite appearance as well as to formulate the theoretically optimal cellulite treatment strategy.

KEYWORDS

Cellulite; Pathophysiology; Adipose Fibrosis; Hyaluronan; Optimal Treatment Strategy

Share and Cite:

I. Kruglikov, "The Pathophysiology of Cellulite: Can the Puzzle Eventually Be Solved?," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 2 No. 1, 2012, pp. 1-7. doi: 10.4236/jcdsa.2012.21001.

Cited by

[1]	Kontroversen in der ?sthetischen Medizin–1. Inwieweit stimmen die Grundlagen?


[2]	Pathophysiology of cellulite: Possible involvement of selective endotoxemia
	Obesity Reviews, 2022

[3]	Long‐term improvement in the appearance of hypertrophic scars following a single treatment with acoustic subcision—A single center proof‐of‐concept study
	Lasers in Surgery and …, 2022

[4]	Vakuuminio masažo taurele ir kūno įvyniojimo su anticeliulitinėmis medžiagomis poveikis celiulitui
	Verslas, technologijos, biomedicina: inovacijų …, 2021

[5]	characterization and pharmacological evaluation of Anti-cellulite Herbal product (s) Encapsulated in 3D-Fabricated polymeric Microneedles
	2020

[6]	Shock Wave Therapy for Wound Healing and Scar Treatment
	2020

[7]	The effects of shock wave therapy applied on hypertrophic burn scars: a randomised controlled trial
	2020

[8]	Drug delivery systems integrated with conventional and advanced treatment approaches toward cellulite reduction
	Journal of Drug Delivery Science …, 2020

[9]	PENGUJIAN PENETRASI IN-VITRO SEDIAAN GEL, KRIM, GEL-KRIM EKSTRAK BIJI KOPI (Coffea arabica L.) SEBAGAI ANTISELULIT
	2019

[10]	Structural Gender Dimorphism and the Biomechanics of the Gluteal Subcutaneous Tissue: Implications for the Pathophysiology of Cellulite
	2019

[11]	Pemanfaatan Biji Kopi Sebagai Antiselulit
	2019

[12]	OBTAINING AND CHARACTERIZATION OF SOME EMULSIONS BASED ON COLLAGEN HYDROLYSATE AND NATURAL EXTRACTS WITH A POTENTIAL ANTICELLULITIC ACTION
	U.P.B. Sci. Bull., Series B, 2019

[13]	OBTAINING AND CHARACTERIZATION OF SOME EMULSIONS BASED ON COLLAGEN HYDROLYSATE AND NATURAL EXTRACTS WITH A POTENTIAL …
	2019

[14]	Efeitos das ondas de choque extracorpórea no fibro edema gelóide (celulite)
	2018

[15]	FORMULASI SEDIAAN GEL, KRIM, GEL-KRIM EKSTRAK BIJI KOPI (Coffea arabica L.) SEBAGAI ANTISELULIT
	2018

[16]	COLLAGEN AND ITS ROLE AS “THE GOOD, THE BAD AND THE UGLY” IN CELLULITE PATHOGENESIS AND TREATMENT
	2018

[17]	PERBEDAAN KARAKTERISTIK DERMATOGLIFI UJUNG JARI DAN TELAPAK TANGAN PEREMPUAN ETNIS MINANGKABAU YANG MENDERITA SELULIT …
	2018

[18]	Clinical evaluation of simultaneously applied monopolar radiofrequency and targeted pressure energy as a new method for noninvasive treatment of cellulite in …
	Journal of cosmetic dermatology, 2018

[19]	LA NUTRACEUTICA AL FEMMINILE: ASPETTI ATTUALI E PROSPETTIVE FUTURE Nutraceuticals and women's health: current aspects and future …
	2017

[20]	LA NUTRACEUTICA AL FEMMINILE: ASPETTI ATTUALI E PROSPETTIVE FUTURE Nutraceuticals and women's health: current aspects and future …
	2017

[21]	Физические и физиологические эффекты вакуумного массажа в различных слоях кожи
	2017

[22]	Perfil dos pacientes em tratamentos estéticos para lipodistrofia e lipodistrofia ginóide nos laboratórios de cosmetologia e estética da Universidade do Sul de Santa …
	2017

[23]	Outcomes following operative vs. non-operative management of blunt traumatic pancreatic injuries: a retrospective multi-institutional study
	2016

[24]	Myoprotective effects of bFGF on skeletal muscle injury in pressure-related deep tissue injury in rats
	2016

[25]	The Facial Adipose Tissue: A Revision
	Facial Plast Surgery, 2016

[26]	Processos degenerativos do tecido cutâneo
	2016

[27]	The physical and physiological effects of vacuum massage on the different skin layers: a current status of the literature
	2016

[28]	Therapeutic approaches to cellulite
	Seminars in Cutaneous Medicine and Surgery, 2015

[29]	Assessment of an anti-cellulite cream: A randomized, double-blind, placebo controlled, right-left comparison, clinical trial
	2015

[30]	Therapeutic approaches to cellulite.
	Seminars in Cutaneous Medicine and Surgery, 2015

[31]	Évaluation de l'efficacité d'un gel topique intégral visant à réduire l'apparence de la cellulite: résultats d'une étude clinique randomisée, à double-insu, contre placebo
	2014

[32]	an integral topical gel for cellulite reduction: results from a double-blind, randomized, placebo-controlled evaluation of efficacy
	Clinical, cosmetic and investigational dermatology, 2014

[33]	CONTROVERSIES IN AESTHETIC MEDICINE: 4. ENIGMA OF CELLULITE
	IL Kruglikov - kosmetischemedizin-online.de, 2014

[34]	General Theory of Body Contouring: 2. Modulation of Mechanical Properties of Subcutaneous Fat Tissue
	Journal of Cosmetics, Dermatological Sciences and Applications, 2014

[35]	General Theory of Body Contouring: 1. Processes of Quick and Slow Modulation of Subcutaneous Fat Tissue
	Journal of Cosmetics, Dermatological Sciences and Applications, 2014

[36]	Use of CPT-1 Modulators and Compositions Thereof
	2013

[37]	Kontroversen in der ästhetischen Medizin 4. Enigma der Cellulite
	2013

[38]	Method of evaluating cellulite and method of evaluating cellulite-effective drug using fibulin-3 and/or sarcoglycan gamma as an indicator
	2012

[39]	Аппаратные методы против целлюлита


[40]	Évaluation de l'efficacité d'un gel topique intégral visant à réduire l'apparence de la cellulite: résultats d'une étude clinique randomisée, à double-insu …
	CCE du Québec

Journals Menu

Follow SCIRP

	+1 323-425-8868
	customer@scirp.org
	+86 18163351462(WhatsApp)
	1655362766

	Paper Publishing WeChat

Journals Menu

Home

About SCIRP

Service

Policies