Journal of Cancer Therapy

Volume 15, Issue 3 (March 2024)

ISSN Print: 2151-1934   ISSN Online: 2151-1942

Google-based Impact Factor: 0.30  Citations  h5-index & Ranking

Effect of Cognitive Behavioral Intervention on Plasma Cortisol in Patients with Breast Cancer PTSD

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DOI: 10.4236/jct.2024.153007    43 Downloads   116 Views  
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ABSTRACT

Objective: To investigate the effect of cognitive behavioral intervention on plasma cortisol in patients with breast cancer PTSD before surgery. Methods: SCL-90, EPQ-N and cognitive behavior intervention were performed on 30 patients with PTSD, 30 patients without PTSD and 30 normal subjects, and their fasting blood was collected to analyze cortisol in the morning. Results: The scores of SCL-90 and EPQ-N in patients with breast cancer PTSD were significantly higher than those in non-PTSD patients and normal subjects (P < 0.01). After cognitive behavioral intervention, the plasma cortisol level of breast cancer PTSD patients was significantly decreased (P < 0.05). Conclusion: Compared with non-PTSD breast cancer patients and normal control group, breast cancer PTSD patients had more serious psychological problems, worse emotional stability and higher plasma cortisol level. Cognitive-behavioral intervention can effectively reduce plasma cortisol levels in breast cancer patients with PTSD.

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Zhou, Y. and Guo, M. (2024) Effect of Cognitive Behavioral Intervention on Plasma Cortisol in Patients with Breast Cancer PTSD. Journal of Cancer Therapy, 15, 62-70. doi: 10.4236/jct.2024.153007.

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