Author(s)

Camara Mamady, Barry Souleymane Djigué, Dore Male^*, Toure Mohamed Lamine, Diallo Mohamed Tafsir, Toure Laïla, Youla Seny, Konate Ibrahimasory, Barry Louceny Fatoumata, Camara Mohamed Salif, Camara Idrissa, Doumbouya Idrissa, Djibo Hamani Bachir, Conde Mohamed Lamine, Cisse Fodé Abass

Department of Neurology, Ignace Deen National Hospital, Conakry, Guinea.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease deadly. In Africa, little data exists on this condition and the form familial is the most common with a younger age of onset. Our observations relate to three brothers, born from a consanguineous marriage. The diagnosis of amyotrophic lateral sclerosis was certain placed in all patients according to the criteria of Awaji. The average age of patients was 16.66 years, and the average age of onset of symptoms was 10.33 years old. The female gender was the most represented with a sex ratio of 0.5. Our patients benefited from rilusole, vitamin D and physiotherapy. A only patient presented with dysphagia. However, no cases have been observed at this day.

ALS, Familial, Juvenile

Mamady, C. , Djigué, B. , Male, D. , Lamine, T. , Tafsir, D. , Laïla, T. , Seny, Y. , Ibrahimasory, K. , Fatoumata, B. , Salif, C. , Idrissa, C. , Idrissa, D. , Bachir, D. , Lamine, C. and Abass, C. (2023) Familial Lateral Sclerosis with Juvenile Onset: About 3 Cases and Review of the Literature. Journal of Biosciences and Medicines, 11, 55-62. doi: 10.4236/jbm.2023.1110006.