Transcriptional Features of Cattle Visceral and Subcutaneous Adipose Tissues: A Study of RNA-seq ()
Affiliation(s)
1Office of Academic Affairs, Hebei North University, Zhangjiakou, China.
2Department of Laboratory Animal Center, Hebei North University, Zhangjiakou, China.
3Key Laboratory of Experimental Animals of Hebei Province, Shijiazhuang, China.
4Hebei North University, Zhangjiakou, China.
ABSTRACT
Visceral
and subcutaneous are the two major types of bovine adipose tissues, and they show metabolic and functional differences
according to their distribution, exploring the transcriptional features
of visceral and subcutaneous adipose tissues
is necessary. In the present study, we conducted RNA-seq analysis to compare the transcriptome between visceral
(great omental) and subcutaneous
(backfat) adipose tissues from Chinese Simmental cattle and validate them by qRT-PCR. We found that 5864 genes were differentially
expressed between two tissues, including 2979 up-regulated and 2885
down-regulated in visceral adipose tissue. Functional analysis
revealed a variety of differentially expressed genes (DEGs) involved in lipid
metabolism and immune response processes. This may provide valuable information
to further our understanding of the complexity
of gene regulation governing the physiology of different fat depots. This
work highlighted potential genes regulating lipid metabolism and immune
responses; it may contribute to a better understanding of the metabolic and
functional differences between visceral and subcutaneous adipose tissues.
Share and Cite:
Duan, X. , Liu, Y. , Zhang, X. and Zhao, H. (2022) Transcriptional Features of Cattle Visceral and Subcutaneous Adipose Tissues: A Study of RNA-seq.
Open Journal of Animal Sciences,
12, 441-453. doi:
10.4236/ojas.2022.123033.
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