Author(s)

Hala Altohame Khalaf Allah¹, Gad Allah Modawe², Abd Elkarim A. Abdrabo^1*

¹Clinical Chemistry Department, Faculty of Medical Laboratory Sciences-Al-Neelain University, Khartoum, Sudan.
²Biochemistry Department, Faculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman, Sudan.

Background: Diabetes mellitus (DM) is a common chronic disease; it is associated with alterations of blood glucose and lipid profile. Current evidence indicated beneficial effects of some medicinal herbs on metabolic parameters. Aim: The aim of this study was to investigate the effect of Nigella Sativa (NS) supplementation on blood glucose and lipid profile levels among type 2 DM Sudanese patients. Materials and Methods: the experimental study was conducted at Gezira state-Khartoum during the period from November 2019 to February 2020. Forty-five diabetic patients were randomly selected. Study population was classified into three groups; each contained 15 patients; glucose and lipid profile were estimated in all participants three times, the first one in day 0, the second after 15 days of daily intake of NS and the last sample after 30 days. Group 1 was given NS at concentration of 1 gram, and group 2 was given NS at concentration of 2 grams, while group 3 was given at concentration of 3 grams. Results: The included patients in the groups used NS with different dose, showed significant (P < 0.05) improvement with reference to blood glucose, while there was no significant improvement of lipid profile in all groups. Conclusion: Using regular NS can improve blood glucose level but has no effect on serum lipids. Concentration of two grams of NS has a better effect on blood glucose control.

Diabetes, Glucose, Herbal Medicine, Lipid Profile

Allah, H.A.K., Modawe, G.A. and Abdrabo, A.E.A. (2021) Biochemical Effect of Nigella sativa (Black Cumin) on Glucose and Lipid Profile among Sudanese Diabetic Patients. Open Access Library Journal, 8, 1-8. doi: 10.4236/oalib.1107500.